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2 changes: 1 addition & 1 deletion databases/charmd/output/metadata.json
Original file line number Diff line number Diff line change
Expand Up @@ -9,7 +9,7 @@
"description": "Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database (CHARMD): https://www.unilim.fr/cnr-herpesvirus/outils/codexmv/.",
"maintainer_update": "2026-09-21",
"license": "CC-BY-NC-4.0",
"tsv_checksum": "sha256:18567a6cc775256a4be8ce343e147bc2227fd4199221eb0b8c5442da0daf1820",
"tsv_checksum": "sha256:c1ef3789e9903226933a6ededa0d0dbe86fb313c58cb69434bcb4698b0d653ca",
"interpretation_algorithms": [
{
"name": "drug_groups",
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4 changes: 2 additions & 2 deletions databases/charmd/output/non-migrated-rules.txt
Original file line number Diff line number Diff line change
Expand Up @@ -19,7 +19,7 @@ indel_undeterministic 975 UL54 D981del2 GCV Deletion D981del2 specifies a length
indel_undeterministic 398 UL54 in884T Insertion in884T has no anchor AA; cannot derive a deterministic reference | Observation: Natural polymorphism
indel_undeterministic 401 UL54 in885S Insertion in885S has no anchor AA; cannot derive a deterministic reference | Observation: Natural polymorphism
indel_undeterministic 402 UL54 in885T Insertion in885T has no anchor AA; cannot derive a deterministic reference | Observation: Natural polymorphism
indel_undeterministic 573 UL97 591-607del GCV Range deletion 591-607del supplies no deleted sequence; deleted block cannot be derived without the reference sequence | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID :
indel_undeterministic 573 UL97 591-607del GCV Range deletion 591-607del supplies no deleted sequence; deleted block cannot be derived without the reference sequence | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer
missing_antiviral 18 UL54 E235G ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable
missing_antiviral 284 UL54 F718L ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable
missing_antiviral 285 UL54 F718S ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable
Expand All @@ -29,6 +29,6 @@ missing_antiviral 42 UL54 N345S ResPro requires antiviral; CHARMD row was retai
missing_antiviral 210 UL54 R581H ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable
missing_antiviral 105 UL54 V482G ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable
missing_antiviral 48 UL54 Y380C ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable
missing_antiviral 621 UL97 D605E ResPro requires antiviral; CHARMD row was retained in the audit only | Observation: IS50 : < 2.2 according to Chou 2020 :
missing_antiviral 621 UL97 D605E ResPro requires antiviral; CHARMD row was retained in the audit only | Observation: IS50 : < 2.2 according to Chou 2020
missing_antiviral 630 UL97 G623S ResPro requires antiviral; CHARMD row was retained in the audit only
missing_antiviral 634 UL97 V665I ResPro requires antiviral; CHARMD row was retained in the audit only
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