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Human survival post-LGM relied on adaptation, cooperation, and innovation. Neanderthal and Denisovan genes shaped immunity and metabolism, but uniform modern diets clash with these traits, fueling chronic disease. Embracing diversity can drive health and resilience.
Symptom-level analysis of inflammatory biomarkers and depression in NHANES (n=1,689): weighted logistic regression, k-means clustering, and ML classification testing which PHQ-9 symptoms show the strongest associations with hsCRP, WBC, NLR, albumin, and ferritin.
Computational target discovery + antigen-specific therapeutic design for inflammatory/immune disorders (EGIDs, celiac, IBD, autoimmune). Bundles the omics-mining, pMHC-epitope, and systematic-review methodology with DOI-verification and presentation-
Code for Jonsson*, Zhang*, et al, TteK (Granzyme K+ CD8 T cells), Science Translational Medicine, 2022: the core population of inflamed human tissue-associated CD8 T cells.