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Regenie-Nextflow-pipeline for QTL analysis

Regenie example workflow

  • Analysing multiple phenotypes at the same time
  • Using quantitative traits
  • Outputting the results as one zip file for each phenotype

Mandatory input parameters in nextflow.config file

  • params.step1_bgen : bgen file for step 1
  • params.step2_bgen : bgen file for step 2
  • params.sample : .sample file for step 1 and step 2
  • params.phenotype_file : phenotypes file , for more details about the format, review regiene documentations
  • params.included_phenotype_ids : tab separated file of phenotypes to include in the analysis (in one column)
  • params.covariate_file : covariates file , for more details about the format, review regiene documentations
  • params.covariate_list : comma separated list of covariates to include in the analysis
  • params.outdir : directory of the output
  • params.prefix : name of the root output file

Use "-entry step2_only" to only run step 2.

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