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K97fs Zebrafish Analysis

  • Analysis code for the research in the manuscript Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2.

  • Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2 Hin N, Newman M, Kaslin J, Douek AM, Lumsden A, et al. (2020) Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. PLOS ONE 15(1): e0227258. https://doi.org/10.1371/journal.pone.0227258

  • The analysis is divided into 5 .Rmd notebooks corresponding to Differential Gene Expression Analysis, Differential Protein Abundance Analysis, Gene Set Testing Analysis, Enrichment Analysis, and Weighted Gene Co-Expression Network Analysis.

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Code to reproduce analyses in "Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2" (Hin & Newman et al. 2020).

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