diff --git a/databases/charmd/output/metadata.json b/databases/charmd/output/metadata.json index 91bf1d8..b540eb9 100644 --- a/databases/charmd/output/metadata.json +++ b/databases/charmd/output/metadata.json @@ -9,7 +9,7 @@ "description": "Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database (CHARMD): https://www.unilim.fr/cnr-herpesvirus/outils/codexmv/.", "maintainer_update": "2026-09-21", "license": "CC-BY-NC-4.0", - "tsv_checksum": "sha256:18567a6cc775256a4be8ce343e147bc2227fd4199221eb0b8c5442da0daf1820", + "tsv_checksum": "sha256:c1ef3789e9903226933a6ededa0d0dbe86fb313c58cb69434bcb4698b0d653ca", "interpretation_algorithms": [ { "name": "drug_groups", diff --git a/databases/charmd/output/non-migrated-rules.txt b/databases/charmd/output/non-migrated-rules.txt index cfda507..b25b5f5 100644 --- a/databases/charmd/output/non-migrated-rules.txt +++ b/databases/charmd/output/non-migrated-rules.txt @@ -19,7 +19,7 @@ indel_undeterministic 975 UL54 D981del2 GCV Deletion D981del2 specifies a length indel_undeterministic 398 UL54 in884T Insertion in884T has no anchor AA; cannot derive a deterministic reference | Observation: Natural polymorphism indel_undeterministic 401 UL54 in885S Insertion in885S has no anchor AA; cannot derive a deterministic reference | Observation: Natural polymorphism indel_undeterministic 402 UL54 in885T Insertion in885T has no anchor AA; cannot derive a deterministic reference | Observation: Natural polymorphism -indel_undeterministic 573 UL97 591-607del GCV Range deletion 591-607del supplies no deleted sequence; deleted block cannot be derived without the reference sequence | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +indel_undeterministic 573 UL97 591-607del GCV Range deletion 591-607del supplies no deleted sequence; deleted block cannot be derived without the reference sequence | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer missing_antiviral 18 UL54 E235G ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable missing_antiviral 284 UL54 F718L ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable missing_antiviral 285 UL54 F718S ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable @@ -29,6 +29,6 @@ missing_antiviral 42 UL54 N345S ResPro requires antiviral; CHARMD row was retai missing_antiviral 210 UL54 R581H ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable missing_antiviral 105 UL54 V482G ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable missing_antiviral 48 UL54 Y380C ResPro requires antiviral; CHARMD row was retained in the audit only | Marker transfer: Recombinant | Observation: Victor trial , before any exposure | Viability: Non viable -missing_antiviral 621 UL97 D605E ResPro requires antiviral; CHARMD row was retained in the audit only | Observation: IS50 : < 2.2 according to Chou 2020 : +missing_antiviral 621 UL97 D605E ResPro requires antiviral; CHARMD row was retained in the audit only | Observation: IS50 : < 2.2 according to Chou 2020 missing_antiviral 630 UL97 G623S ResPro requires antiviral; CHARMD row was retained in the audit only missing_antiviral 634 UL97 V665I ResPro requires antiviral; CHARMD row was retained in the audit only diff --git a/databases/charmd/output/rules.tsv b/databases/charmd/output/rules.tsv index c429252..5c6457d 100644 --- a/databases/charmd/output/rules.tsv +++ b/databases/charmd/output/rules.tsv @@ -94,7 +94,7 @@ HCMVUL27 X17403.1 229 E D foscarnet sensitive PMID:19704169 CHARMD Source origi HCMVUL27 X17403.1 229 E D ganciclovir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL27 X17403.1 229 E D letermovir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL27 X17403.1 229 E D maribavir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism -HCMVUL27 X17403.1 233 R S maribavir susceptible 0.2 PMID:30040968,PMID:22664236,PMID:15194788 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: Yield reduction assay, SEAP | Observation: Other publication ID : , +HCMVUL27 X17403.1 233 R S maribavir susceptible 0.2 PMID:30040968,PMID:22664236,PMID:15194788 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: Yield reduction assay, SEAP HCMVUL27 X17403.1 269 A T maribavir low-level resistance 2 PMID:18981262 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: Yield reduction assay, SEAP HCMVUL27 X17403.1 289 N D brincidofovir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL27 X17403.1 289 N D cidofovir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism @@ -159,7 +159,7 @@ HCMVUL27 X17403.1 313 H Y foscarnet sensitive PMID:19704169 CHARMD Source origi HCMVUL27 X17403.1 313 H Y ganciclovir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL27 X17403.1 313 H Y letermovir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL27 X17403.1 313 H Y maribavir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism -HCMVUL27 X17403.1 335 L P maribavir high-level resistance 23 PMID:14565505,PMID:14557635 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: Yield reduction assay | Observation: Other publication ID : +HCMVUL27 X17403.1 335 L P maribavir high-level resistance 23 PMID:14565505,PMID:14557635 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: Yield reduction assay HCMVUL27 X17403.1 344 G D maribavir susceptible 0.9 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL27 X17403.1 351 D N brincidofovir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL27 X17403.1 351 D N cidofovir sensitive PMID:19704169 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism @@ -342,7 +342,7 @@ HCMVUL51 X17403.1 70 L I foscarnet sensitive PMID:35690130 CHARMD Source origin HCMVUL51 X17403.1 70 L I ganciclovir sensitive PMID:35690130 CHARMD Source origin: Clincial isolate | Observation: Natural polymorphism HCMVUL51 X17403.1 70 L I letermovir sensitive PMID:35690130 CHARMD Source origin: Clincial isolate | Observation: Natural polymorphism HCMVUL51 X17403.1 70 L I maribavir sensitive PMID:35690130 CHARMD Source origin: Clincial isolate | Observation: Natural polymorphism -HCMVUL51 X17403.1 91 P S letermovir low-level resistance 2.1 PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : +HCMVUL51 X17403.1 91 P S letermovir low-level resistance 2.1 PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP HCMVUL51 X17403.1 95 A V letermovir high-level resistance 13.8 PMID:35690130 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: marker transfer HCMVUL51 X17403.1 113 V L letermovir susceptible 1.5 PMID:35690130 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Observation: Natural polymorphism HCMVUL51 X17403.1 153 S P brincidofovir sensitive PMID:35690130 CHARMD Source origin: Reference strain | Observation: Natural polymorphism @@ -497,9 +497,9 @@ HCMVUL54 X17403.1 288 D N ganciclovir susceptible 1.2 PMID:24273181 CHARMD Marke HCMVUL54 X17403.1 290 S R cidofovir susceptible 1.35 PMID:27940027 CHARMD Fold IC50 values: 1.3, 1.4; mean displayed | Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 290 S R foscarnet low-level resistance 2.25 PMID:27940027 CHARMD Fold IC50 values: 2.2, 2.3; mean displayed | Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 290 S R ganciclovir susceptible 1.6 PMID:27940027 CHARMD Fold IC50 values: 1.5, 1.7; mean displayed | Source origin: Laboratory strain, Clinical Isolate -HCMVUL54 X17403.1 301 D N cidofovir intermediate 3 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 301 D N foscarnet susceptible 0.5 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 301 D N ganciclovir low-level resistance 2.6 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 301 D N cidofovir intermediate 3 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 301 D N foscarnet susceptible 0.5 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 301 D N ganciclovir low-level resistance 2.6 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 303 E D brincidofovir high-level resistance 9.7 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant HCMVUL54 X17403.1 303 E D cidofovir high-level resistance 16 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant HCMVUL54 X17403.1 303 E D foscarnet susceptible 0.8 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant @@ -567,44 +567,44 @@ HCMVUL54 X17403.1 394 L F maribavir sensitive PMID:24273181 CHARMD Observation: HCMVUL54 X17403.1 396 F L cidofovir susceptible 1.5 PMID:24273181 CHARMD Marker transfer: Recombinant HCMVUL54 X17403.1 396 F L foscarnet susceptible 0.9 PMID:24273181 CHARMD Marker transfer: Recombinant HCMVUL54 X17403.1 396 F L ganciclovir susceptible 1.4 PMID:24273181 CHARMD Marker transfer: Recombinant -HCMVUL54 X17403.1 408 N D cidofovir high-level resistance 5.6 PMID:9621055,PMID:24903568,PMID:9207351,PMID:15258973,PMID:20961907,PMID:26098499,PMID:17043128,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 408 N D foscarnet susceptible 1.3 PMID:9621055,PMID:24903568,PMID:9207351,PMID:15258973,PMID:20961907,PMID:26098499,PMID:17043128,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 408 N D ganciclovir intermediate 4.9 PMID:9621055,PMID:24903568,PMID:9207351,PMID:15258973,PMID:20961907,PMID:26098499,PMID:17043128,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 408 N D cidofovir high-level resistance 5.6 PMID:9621055,PMID:24903568,PMID:9207351,PMID:15258973,PMID:20961907,PMID:26098499,PMID:17043128,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 408 N D foscarnet susceptible 1.3 PMID:9621055,PMID:24903568,PMID:9207351,PMID:15258973,PMID:20961907,PMID:26098499,PMID:17043128,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 408 N D ganciclovir intermediate 4.9 PMID:9621055,PMID:24903568,PMID:9207351,PMID:15258973,PMID:20961907,PMID:26098499,PMID:17043128,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 408 N H cidofovir intermediate 3.3 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 408 N H foscarnet intermediate 3 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 408 N H ganciclovir low-level resistance 2 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 408 N K brincidofovir high-level resistance 11 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant -HCMVUL54 X17403.1 408 N K cidofovir high-level resistance 21 PMID:17043128,PMID:24903568,PMID:20961907,PMID:15258974 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 408 N K foscarnet susceptible 0.7 PMID:17043128,PMID:24903568,PMID:20961907,PMID:15258975 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 408 N K ganciclovir intermediate 4.2 PMID:17043128,PMID:24903568,PMID:20961907,PMID:15258973 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 408 N K cidofovir high-level resistance 21 PMID:17043128,PMID:24903568,PMID:20961907,PMID:15258974 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 408 N K foscarnet susceptible 0.7 PMID:17043128,PMID:24903568,PMID:20961907,PMID:15258975 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 408 N K ganciclovir intermediate 4.2 PMID:17043128,PMID:24903568,PMID:20961907,PMID:15258973 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 408 N S cidofovir high-level resistance 7.5 PMID:23415883 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 408 N S foscarnet susceptible 1 PMID:23415883 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 408 N S ganciclovir intermediate 3.1 PMID:23415883 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 410 N K cidofovir intermediate 3 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 410 N K foscarnet susceptible 0.8 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 410 N K ganciclovir low-level resistance 2.9 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F C cidofovir high-level resistance 18 PMID:9291334,PMID:11595579,PMID:24903568,PMID:9207351,PMID:23985917 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F C foscarnet susceptible 1.2 PMID:9291334,PMID:11595579,PMID:24903568,PMID:9207351,PMID:23985918 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F C ganciclovir intermediate 4.2 PMID:9291334,PMID:11595579,PMID:24903568,PMID:9207351,PMID:23985916 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F L cidofovir high-level resistance 9.4 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F L foscarnet susceptible 1.1 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F L ganciclovir intermediate 4.6 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F S cidofovir high-level resistance 13 PMID:21295516,PMID:22001948,PMID:24903568,PMID:12198610 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F S foscarnet susceptible 0.8 PMID:21295516,PMID:22001948,PMID:24903568,PMID:12198611 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F S ganciclovir high-level resistance 5.3 PMID:21295516,PMID:22001948,PMID:24903568,PMID:12198609 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F V cidofovir high-level resistance 15.5 PMID:9621055,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F V foscarnet susceptible 1.1 PMID:9621055,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 412 F V ganciclovir intermediate 4.3 PMID:9621055,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 413 D A cidofovir high-level resistance 11 PMID:17157554,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 413 D A foscarnet susceptible 0.8 PMID:17157554,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 413 D A ganciclovir high-level resistance 6.5 PMID:17157554,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 410 N K cidofovir intermediate 3 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 410 N K foscarnet susceptible 0.8 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 410 N K ganciclovir low-level resistance 2.9 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F C cidofovir high-level resistance 18 PMID:9291334,PMID:11595579,PMID:24903568,PMID:9207351,PMID:23985917 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F C foscarnet susceptible 1.2 PMID:9291334,PMID:11595579,PMID:24903568,PMID:9207351,PMID:23985918 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F C ganciclovir intermediate 4.2 PMID:9291334,PMID:11595579,PMID:24903568,PMID:9207351,PMID:23985916 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F L cidofovir high-level resistance 9.4 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F L foscarnet susceptible 1.1 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F L ganciclovir intermediate 4.6 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F S cidofovir high-level resistance 13 PMID:21295516,PMID:22001948,PMID:24903568,PMID:12198610 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F S foscarnet susceptible 0.8 PMID:21295516,PMID:22001948,PMID:24903568,PMID:12198611 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F S ganciclovir high-level resistance 5.3 PMID:21295516,PMID:22001948,PMID:24903568,PMID:12198609 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F V cidofovir high-level resistance 15.5 PMID:9621055,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F V foscarnet susceptible 1.1 PMID:9621055,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 412 F V ganciclovir intermediate 4.3 PMID:9621055,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 413 D A cidofovir high-level resistance 11 PMID:17157554,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 413 D A foscarnet susceptible 0.8 PMID:17157554,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 413 D A ganciclovir high-level resistance 6.5 PMID:17157554,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 413 D D413del brincidofovir high-level resistance 5.2 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant HCMVUL54 X17403.1 413 D D413del cidofovir high-level resistance 5.8 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant HCMVUL54 X17403.1 413 D D413del foscarnet susceptible 1.3 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant HCMVUL54 X17403.1 413 D D413del ganciclovir intermediate 3.8 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant -HCMVUL54 X17403.1 413 D E cidofovir intermediate 4.3 PMID:12825168,PMID:24903568,PMID:20961907,PMID:9129071 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 413 D E foscarnet susceptible 0.8 PMID:12825168,PMID:24903568,PMID:20961907,PMID:9129072 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 413 D E ganciclovir intermediate 4.8 PMID:12825168,PMID:24903568,PMID:20961907,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 413 D E cidofovir intermediate 4.3 PMID:12825168,PMID:24903568,PMID:20961907,PMID:9129071 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 413 D E foscarnet susceptible 0.8 PMID:12825168,PMID:24903568,PMID:20961907,PMID:9129072 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 413 D E ganciclovir intermediate 4.8 PMID:12825168,PMID:24903568,PMID:20961907,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 413 D N cidofovir high-level resistance 10 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 413 D N foscarnet susceptible 1 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 413 D N ganciclovir intermediate 3.8 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells @@ -680,60 +680,60 @@ HCMVUL54 X17403.1 483 V A foscarnet sensitive PMID:24273181 CHARMD Observation: HCMVUL54 X17403.1 483 V A ganciclovir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure HCMVUL54 X17403.1 483 V A letermovir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure HCMVUL54 X17403.1 483 V A maribavir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure -HCMVUL54 X17403.1 488 P R cidofovir high-level resistance 7.9 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 488 P R foscarnet susceptible 0.6 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 488 P R ganciclovir intermediate 3.5 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 488 P R cidofovir high-level resistance 7.9 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 488 P R foscarnet susceptible 0.6 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 488 P R ganciclovir intermediate 3.5 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 492 A D cidofovir susceptible 1.36 PMID:27058773 CHARMD Marker transfer: Recombinant | Assay details: Modified plaque reduction assay | Observation: Natural polymorphism HCMVUL54 X17403.1 492 A D foscarnet susceptible 1.45 PMID:27058773 CHARMD Marker transfer: Recombinant | Assay details: Modified plaque reduction assay | Observation: Natural polymorphism HCMVUL54 X17403.1 492 A D ganciclovir susceptible 1.35 PMID:27058773 CHARMD Marker transfer: Recombinant | Assay details: Modified plaque reduction assay | Observation: Natural polymorphism HCMVUL54 X17403.1 493 K N cidofovir low-level resistance 2 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 493 K N foscarnet intermediate 3.3 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 493 K N ganciclovir intermediate 4.1 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate -HCMVUL54 X17403.1 495 N K cidofovir susceptible 1.1 PMID:16856628,PMID:18992772,PMID:24903568,PMID:27940027 CHARMD Fold IC50 values: 1.1, 1.2, 1; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID: | Source origin: Laboratory strain, Clinical Isolate -HCMVUL54 X17403.1 495 N K foscarnet low-level resistance 2.83333 PMID:16856628,PMID:18992772,PMID:24903568,PMID:27940027 CHARMD Fold IC50 values: 3.4, 2.5, 2.6; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID: | Source origin: Laboratory strain, Clinical Isolate -HCMVUL54 X17403.1 495 N K ganciclovir susceptible 1.26667 PMID:16856628,PMID:18992772,PMID:24903568,PMID:27940027 CHARMD Fold IC50 values: 1.1, 1.3, 1.4; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID: | Source origin: Laboratory strain, Clinical Isolate +HCMVUL54 X17403.1 495 N K cidofovir susceptible 1.1 PMID:16856628,PMID:18992772,PMID:24903568,PMID:27940027 CHARMD Fold IC50 values: 1.1, 1.2, 1; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain, Clinical Isolate +HCMVUL54 X17403.1 495 N K foscarnet low-level resistance 2.83333 PMID:16856628,PMID:18992772,PMID:24903568,PMID:27940027 CHARMD Fold IC50 values: 3.4, 2.5, 2.6; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain, Clinical Isolate +HCMVUL54 X17403.1 495 N K ganciclovir susceptible 1.26667 PMID:16856628,PMID:18992772,PMID:24903568,PMID:27940027 CHARMD Fold IC50 values: 1.1, 1.3, 1.4; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 497 P S cidofovir low-level resistance 2.4 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 497 P S foscarnet susceptible 0.8 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 497 P S ganciclovir susceptible 1.9 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 498 N S cidofovir susceptible 1.8 PMID:41482062 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 498 N S foscarnet susceptible 1.7 PMID:41482062 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 498 N S ganciclovir susceptible 1.7 PMID:41482062 CHARMD Source origin: Clinical Isolate -HCMVUL54 X17403.1 500 K N cidofovir intermediate 3 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 500 K N foscarnet susceptible 1.2 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 500 K N ganciclovir intermediate 3.2 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 501 L F cidofovir intermediate 3.8 PMID:37506264,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903569 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 501 L F foscarnet susceptible 1.3 PMID:37506264,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903570 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 501 L F ganciclovir low-level resistance 2.6 PMID:37506264,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 501 L I cidofovir high-level resistance 9.1 PMID:9621055,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903569 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 501 L I foscarnet susceptible 1.4 PMID:9621055,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903570 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 501 L I ganciclovir high-level resistance 6 PMID:9621055,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 500 K N cidofovir intermediate 3 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 500 K N foscarnet susceptible 1.2 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 500 K N ganciclovir intermediate 3.2 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 501 L F cidofovir intermediate 3.8 PMID:37506264,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903569 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 501 L F foscarnet susceptible 1.3 PMID:37506264,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903570 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 501 L F ganciclovir low-level resistance 2.6 PMID:37506264,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 501 L I cidofovir high-level resistance 9.1 PMID:9621055,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903569 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 501 L I foscarnet susceptible 1.4 PMID:9621055,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903570 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 501 L I ganciclovir high-level resistance 6 PMID:9621055,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 503 T A cidofovir intermediate 3.7 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 503 T A foscarnet susceptible 1.5 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 503 T A ganciclovir intermediate 3.1 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL54 X17403.1 503 T I cidofovir high-level resistance 6.1 PMID:12825168,PMID:23985916,PMID:15258973,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 503 T I foscarnet susceptible 0.5 PMID:12825168,PMID:23985916,PMID:15258973,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 503 T I ganciclovir low-level resistance 2.9 PMID:12825168,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 503 T I cidofovir high-level resistance 6.1 PMID:12825168,PMID:23985916,PMID:15258973,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 503 T I foscarnet susceptible 0.5 PMID:12825168,PMID:23985916,PMID:15258973,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 503 T I ganciclovir low-level resistance 2.9 PMID:12825168,PMID:23985916,PMID:15258973,PMID:9207351,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 505 A V cidofovir low-level resistance 2 PMID:24273181 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Victor Study HCMVUL54 X17403.1 505 A V foscarnet susceptible 1.1 PMID:24273181 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Victor Study HCMVUL54 X17403.1 505 A V ganciclovir susceptible 1.8 PMID:24273181 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Victor Study -HCMVUL54 X17403.1 513 K E cidofovir high-level resistance 9.1 PMID:9621055,PMID:24903568,PMID:11595579,PMID:9207352 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 513 K E foscarnet susceptible 1.4 PMID:9621055,PMID:24903568,PMID:11595579,PMID:9207353 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 513 K E ganciclovir high-level resistance 5 PMID:9621055,PMID:24903568,PMID:11595579,PMID:9207351 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 513 K N cidofovir high-level resistance 12.5 PMID:9721246,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 513 K N foscarnet susceptible 1.5 PMID:9721246,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 513 K N ganciclovir high-level resistance 6 PMID:9721246,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 513 K E cidofovir high-level resistance 9.1 PMID:9621055,PMID:24903568,PMID:11595579,PMID:9207352 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 513 K E foscarnet susceptible 1.4 PMID:9621055,PMID:24903568,PMID:11595579,PMID:9207353 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 513 K E ganciclovir high-level resistance 5 PMID:9621055,PMID:24903568,PMID:11595579,PMID:9207351 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 513 K N cidofovir high-level resistance 12.5 PMID:9721246,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 513 K N foscarnet susceptible 1.5 PMID:9721246,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 513 K N ganciclovir high-level resistance 6 PMID:9721246,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 513 K Q cidofovir high-level resistance 18 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 513 K Q foscarnet susceptible 1 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 513 K Q ganciclovir high-level resistance 6.6 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL54 X17403.1 513 K R cidofovir high-level resistance 10 PMID:24890586,PMID:9207351 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 513 K R foscarnet susceptible 1.1 PMID:24890586,PMID:9207351 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 513 K R ganciclovir intermediate 3.7 PMID:24890586,PMID:9207351 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 513 K R cidofovir high-level resistance 10 PMID:24890586,PMID:9207351 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 513 K R foscarnet susceptible 1.1 PMID:24890586,PMID:9207351 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 513 K R ganciclovir intermediate 3.7 PMID:24890586,PMID:9207351 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 513 K T cidofovir high-level resistance 19 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 513 K T foscarnet susceptible 1 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 513 K T ganciclovir intermediate 4.9 PMID:32726419 CHARMD Source origin: Clinical Isolate -HCMVUL54 X17403.1 515 D E cidofovir susceptible 1.35 PMID:11050017,PMID:26209398,PMID:41482062 CHARMD Fold IC50 values: 1.6, 1.1; mean displayed | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate -HCMVUL54 X17403.1 515 D E foscarnet low-level resistance 2.75 PMID:11050017,PMID:26209398,PMID:41482062 CHARMD Fold IC50 values: 4.6, 0.9; mean displayed | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate -HCMVUL54 X17403.1 515 D E ganciclovir susceptible 1.85 PMID:11050017,PMID:26209398,PMID:41482062 CHARMD Fold IC50 values: 2.7, 1; mean displayed | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate +HCMVUL54 X17403.1 515 D E cidofovir susceptible 1.35 PMID:11050017,PMID:26209398,PMID:41482062 CHARMD Fold IC50 values: 1.6, 1.1; mean displayed | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate +HCMVUL54 X17403.1 515 D E foscarnet low-level resistance 2.75 PMID:11050017,PMID:26209398,PMID:41482062 CHARMD Fold IC50 values: 4.6, 0.9; mean displayed | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate +HCMVUL54 X17403.1 515 D E ganciclovir susceptible 1.85 PMID:11050017,PMID:26209398,PMID:41482062 CHARMD Fold IC50 values: 2.7, 1; mean displayed | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate HCMVUL54 X17403.1 515 D G brincidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 515 D G cidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 515 D G cyclopropavir sensitive CHARMD Observation: Natural polymorphism @@ -741,15 +741,15 @@ HCMVUL54 X17403.1 515 D G foscarnet sensitive CHARMD Observation: Natural poly HCMVUL54 X17403.1 515 D G ganciclovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 515 D G letermovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 515 D G maribavir sensitive CHARMD Observation: Natural polymorphism -HCMVUL54 X17403.1 515 D Y cidofovir susceptible 1.735 PMID:26872863,PMID:20961907,PMID:30286286 CHARMD Fold IC50 values: 0.87, 2.6; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : | Source origin: Laboratory strain, Clinical Isolate -HCMVUL54 X17403.1 515 D Y foscarnet low-level resistance 2.9 PMID:26872863,PMID:20961907,PMID:30286286 CHARMD Fold IC50 values: 4.7, 1.1; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : | Source origin: Laboratory strain, Clinical Isolate -HCMVUL54 X17403.1 515 D Y ganciclovir intermediate 4.7 PMID:26872863,PMID:20961907,PMID:30286286 CHARMD Fold IC50 values: 6.2, 3.2; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : | Source origin: Laboratory strain, Clinical Isolate +HCMVUL54 X17403.1 515 D Y cidofovir susceptible 1.735 PMID:26872863,PMID:20961907,PMID:30286286 CHARMD Fold IC50 values: 0.87, 2.6; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain, Clinical Isolate +HCMVUL54 X17403.1 515 D Y foscarnet low-level resistance 2.9 PMID:26872863,PMID:20961907,PMID:30286286 CHARMD Fold IC50 values: 4.7, 1.1; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain, Clinical Isolate +HCMVUL54 X17403.1 515 D Y ganciclovir intermediate 4.7 PMID:26872863,PMID:20961907,PMID:30286286 CHARMD Fold IC50 values: 6.2, 3.2; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 516 L P cidofovir high-level resistance 5.9 PMID:30286286 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 516 L P foscarnet susceptible 0.9 PMID:30286286 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 516 L P ganciclovir intermediate 4.4 PMID:30286286 CHARMD Source origin: Clinical Isolate -HCMVUL54 X17403.1 516 L R cidofovir high-level resistance 5.1 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 516 L R foscarnet susceptible 0.8 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 516 L R ganciclovir low-level resistance 2.1 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 516 L R cidofovir high-level resistance 5.1 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 516 L R foscarnet susceptible 0.8 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 516 L R ganciclovir low-level resistance 2.1 PMID:12825168,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 516 L W cidofovir high-level resistance 8.49 PMID:27058773 CHARMD Source origin: Clincial isolate | Assay details: Modified plaque reduction assay HCMVUL54 X17403.1 516 L W foscarnet susceptible 1.22 PMID:27058773 CHARMD Source origin: Clincial isolate | Assay details: Modified plaque reduction assay HCMVUL54 X17403.1 516 L W ganciclovir intermediate 4.2 PMID:27058773 CHARMD Source origin: Clincial isolate | Assay details: Modified plaque reduction assay @@ -760,12 +760,12 @@ HCMVUL54 X17403.1 518 Y C foscarnet sensitive CHARMD Observation: Natural poly HCMVUL54 X17403.1 518 Y C ganciclovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 518 Y C letermovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 518 Y C maribavir sensitive CHARMD Observation: Natural polymorphism -HCMVUL54 X17403.1 521 I T cidofovir high-level resistance 5.1 PMID:18502683,PMID:11050017,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 521 I T foscarnet susceptible 0.8 PMID:18502683,PMID:11050017,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 521 I T ganciclovir low-level resistance 2.1 PMID:18502683,PMID:11050017,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 522 P A cidofovir intermediate 4.1 PMID:18502683,PMID:9129070,PMID:23985916,PMID:24903569 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 522 P A foscarnet susceptible 1 PMID:18502683,PMID:9129070,PMID:23985916,PMID:24903570 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 522 P A ganciclovir intermediate 3 PMID:18502683,PMID:9129070,PMID:23985916,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 521 I T cidofovir high-level resistance 5.1 PMID:18502683,PMID:11050017,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 521 I T foscarnet susceptible 0.8 PMID:18502683,PMID:11050017,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 521 I T ganciclovir low-level resistance 2.1 PMID:18502683,PMID:11050017,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 522 P A cidofovir intermediate 4.1 PMID:18502683,PMID:9129070,PMID:23985916,PMID:24903569 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 522 P A foscarnet susceptible 1 PMID:18502683,PMID:9129070,PMID:23985916,PMID:24903570 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 522 P A ganciclovir intermediate 3 PMID:18502683,PMID:9129070,PMID:23985916,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 522 P L brincidofovir sensitive PMID:18502683 CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 522 P L cidofovir sensitive PMID:18502683 CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 522 P L cyclopropavir sensitive PMID:18502683 CHARMD Observation: Natural polymorphism @@ -773,9 +773,9 @@ HCMVUL54 X17403.1 522 P L foscarnet sensitive PMID:18502683 CHARMD Observation: HCMVUL54 X17403.1 522 P L ganciclovir sensitive PMID:18502683 CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 522 P L letermovir sensitive PMID:18502683 CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 522 P L maribavir sensitive PMID:18502683 CHARMD Observation: Natural polymorphism -HCMVUL54 X17403.1 522 P S cidofovir intermediate 3.6 PMID:9621055 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 522 P S foscarnet susceptible 1.1 PMID:9621055 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 522 P S ganciclovir intermediate 3.1 PMID:9621055,PMID:24903568,PMID:15230476,PMID:12198609,PMID:23985916,PMID:18992772,PMID:11704031,PMID:24890586,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 522 P S cidofovir intermediate 3.6 PMID:9621055 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 522 P S foscarnet susceptible 1.1 PMID:9621055 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 522 P S ganciclovir intermediate 3.1 PMID:9621055,PMID:24903568,PMID:15230476,PMID:12198609,PMID:23985916,PMID:18992772,PMID:11704031,PMID:24890586,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 522 P T cidofovir low-level resistance 2 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 522 P T foscarnet susceptible 1.4 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 522 P T ganciclovir low-level resistance 2.1 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer @@ -788,9 +788,9 @@ HCMVUL54 X17403.1 526 V L ganciclovir high-level resistance 5.5 PMID:25143583 CH HCMVUL54 X17403.1 539 C G cidofovir intermediate 4.4 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 539 C G foscarnet susceptible 1 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 539 C G ganciclovir intermediate 3.1 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 539 C R cidofovir high-level resistance 13.3 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 539 C R foscarnet susceptible 0.7 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 539 C R ganciclovir intermediate 3.2 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 539 C R cidofovir high-level resistance 13.3 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 539 C R foscarnet susceptible 0.7 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 539 C R ganciclovir intermediate 3.2 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 541 Q P brincidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 541 Q P cidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 541 Q P cyclopropavir sensitive CHARMD Observation: Natural polymorphism @@ -810,45 +810,45 @@ HCMVUL54 X17403.1 543 A V ganciclovir low-level resistance 2.1 PMID:41482062 CHA HCMVUL54 X17403.1 545 L F cidofovir high-level resistance 11 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 545 L F foscarnet susceptible 1.2 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 545 L F ganciclovir intermediate 4 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL54 X17403.1 545 L S cidofovir high-level resistance 9.1 PMID:9621055,PMID:19063923,PMID:24903568,PMID:21709106,PMID:16173018 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 545 L S foscarnet susceptible 1.2 PMID:9621055,PMID:19063923,PMID:24903568,PMID:21709106,PMID:16173018 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 545 L S ganciclovir intermediate 3.5 PMID:9621055,PMID:19063923,PMID:24903568,PMID:21709106,PMID:16173018 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 545 L W cidofovir high-level resistance 6.3 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 545 L W foscarnet susceptible 1.3 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 545 L W ganciclovir intermediate 4.9 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 552 T N cidofovir susceptible 1.3 PMID:21709106,PMID:22001948,PMID:27940027 CHARMD Fold IC50 values: 1.2, 1, 1.7; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : | Source origin: Laboratory strain -HCMVUL54 X17403.1 552 T N foscarnet low-level resistance 2.73333 PMID:21709106,PMID:22001948,PMID:27940027 CHARMD Fold IC50 values: 2.6, 2.5, 3.1; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : | Source origin: Laboratory strain -HCMVUL54 X17403.1 552 T N ganciclovir low-level resistance 2.1 PMID:21709106,PMID:22001948,PMID:27940027 CHARMD Fold IC50 values: 1.9, 1.8, 2.6; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : | Source origin: Laboratory strain +HCMVUL54 X17403.1 545 L S cidofovir high-level resistance 9.1 PMID:9621055,PMID:19063923,PMID:24903568,PMID:21709106,PMID:16173018 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 545 L S foscarnet susceptible 1.2 PMID:9621055,PMID:19063923,PMID:24903568,PMID:21709106,PMID:16173018 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 545 L S ganciclovir intermediate 3.5 PMID:9621055,PMID:19063923,PMID:24903568,PMID:21709106,PMID:16173018 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 545 L W cidofovir high-level resistance 6.3 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 545 L W foscarnet susceptible 1.3 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 545 L W ganciclovir intermediate 4.9 PMID:21295516,PMID:22001948,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 552 T N cidofovir susceptible 1.3 PMID:21709106,PMID:22001948,PMID:27940027 CHARMD Fold IC50 values: 1.2, 1, 1.7; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain +HCMVUL54 X17403.1 552 T N foscarnet low-level resistance 2.73333 PMID:21709106,PMID:22001948,PMID:27940027 CHARMD Fold IC50 values: 2.6, 2.5, 3.1; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain +HCMVUL54 X17403.1 552 T N ganciclovir low-level resistance 2.1 PMID:21709106,PMID:22001948,PMID:27940027 CHARMD Fold IC50 values: 1.9, 1.8, 2.6; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain HCMVUL54 X17403.1 552 T S cidofovir low-level resistance 2.7 PMID:35021130 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant HCMVUL54 X17403.1 552 T S foscarnet susceptible 0.5 PMID:35021130 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant HCMVUL54 X17403.1 552 T S ganciclovir intermediate 3 PMID:35021130 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant HCMVUL54 X17403.1 565 L V cidofovir susceptible 1.6 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 565 L V foscarnet intermediate 3.7 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 565 L V ganciclovir susceptible 1.8 PMID:32726419 CHARMD Source origin: Clinical Isolate -HCMVUL54 X17403.1 578 Q H cidofovir low-level resistance 2.3 PMID:21295516,PMID:12637079,PMID:22001948,PMID:24903568,PMID:24183928,PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 578 Q H foscarnet intermediate 4.5 PMID:21295516,PMID:12637079,PMID:22001948,PMID:24903568,PMID:24183928,PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 578 Q H ganciclovir intermediate 3.3 PMID:21295516,PMID:12637079,PMID:22001948,PMID:24903568,PMID:24183928,PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 578 Q L cidofovir susceptible 0.8 PMID:24890586,PMID:26098499 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 578 Q L foscarnet intermediate 3 PMID:24890586,PMID:26098499 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 578 Q L ganciclovir susceptible 1.9 PMID:24890586,PMID:26098499 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 585 S A cidofovir susceptible 1.4 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 585 S A foscarnet low-level resistance 2.7 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 585 S A ganciclovir susceptible 1.5 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 588 D E cidofovir susceptible 1.1 PMID:9621055,PMID:24903568,PMID:9207351 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 588 D E foscarnet low-level resistance 2.3 PMID:9621055,PMID:24903568,PMID:9207351 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 588 D E ganciclovir susceptible 1.3 PMID:9621055,PMID:24903568,PMID:9207351 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 588 D N cidofovir low-level resistance 2.7 PMID:15634973,PMID:24903568,PMID:23985916,PMID:11595579 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 588 D N foscarnet high-level resistance 9 PMID:15634973,PMID:24903568,PMID:23985916,PMID:11595579 CHARMD Fold IC50 values: 9, 3.2-9; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 588 D N ganciclovir intermediate 3.8 PMID:15634973,PMID:24903568,PMID:23985916,PMID:11595579 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 578 Q H cidofovir low-level resistance 2.3 PMID:21295516,PMID:12637079,PMID:22001948,PMID:24903568,PMID:24183928,PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 578 Q H foscarnet intermediate 4.5 PMID:21295516,PMID:12637079,PMID:22001948,PMID:24903568,PMID:24183928,PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 578 Q H ganciclovir intermediate 3.3 PMID:21295516,PMID:12637079,PMID:22001948,PMID:24903568,PMID:24183928,PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 578 Q L cidofovir susceptible 0.8 PMID:24890586,PMID:26098499 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 578 Q L foscarnet intermediate 3 PMID:24890586,PMID:26098499 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 578 Q L ganciclovir susceptible 1.9 PMID:24890586,PMID:26098499 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 585 S A cidofovir susceptible 1.4 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 585 S A foscarnet low-level resistance 2.7 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 585 S A ganciclovir susceptible 1.5 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 588 D E cidofovir susceptible 1.1 PMID:9621055,PMID:24903568,PMID:9207351 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 588 D E foscarnet low-level resistance 2.3 PMID:9621055,PMID:24903568,PMID:9207351 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 588 D E ganciclovir susceptible 1.3 PMID:9621055,PMID:24903568,PMID:9207351 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 588 D N cidofovir low-level resistance 2.7 PMID:15634973,PMID:24903568,PMID:23985916,PMID:11595579 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 588 D N foscarnet high-level resistance 9 PMID:15634973,PMID:24903568,PMID:23985916,PMID:11595579 CHARMD Fold IC50 values: 9, 3.2-9; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 588 D N ganciclovir intermediate 3.8 PMID:15634973,PMID:24903568,PMID:23985916,PMID:11595579 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 590 C F cidofovir susceptible 1.6 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 590 C F foscarnet low-level resistance 2.3 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 590 C F ganciclovir susceptible 1.6 PMID:37506264 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 594 D N cidofovir susceptible 1 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 594 D N foscarnet susceptible 1 PMID:32726419 CHARMD Source origin: Clinical Isolate HCMVUL54 X17403.1 594 D N ganciclovir susceptible 1 PMID:32726419 CHARMD Source origin: Clinical Isolate -HCMVUL54 X17403.1 595 F I cidofovir susceptible 1.2 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 595 F I foscarnet low-level resistance 2 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 595 F I ganciclovir susceptible 1.3 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 595 F I cidofovir susceptible 1.2 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 595 F I foscarnet low-level resistance 2 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 595 F I ganciclovir susceptible 1.3 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 598 P S cidofovir susceptible 1.7 PMID:41482062 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 598 P S foscarnet susceptible 0.7 PMID:41482062 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 598 P S ganciclovir susceptible 1.9 PMID:41482062 CHARMD Source origin: Laboratory strain, Clinical Isolate @@ -1104,15 +1104,15 @@ HCMVUL54 X17403.1 697 Q H foscarnet sensitive PMID:10348781 CHARMD Observation: HCMVUL54 X17403.1 697 Q H ganciclovir sensitive PMID:10348781 CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 697 Q H letermovir sensitive PMID:10348781 CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 697 Q H maribavir sensitive PMID:10348781 CHARMD Observation: Natural polymorphism -HCMVUL54 X17403.1 700 T A cidofovir susceptible 1.5 PMID:9621055,PMID:24903568,PMID:25405808,PMID:9129070,PMID:8627655 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 700 T A foscarnet intermediate 4.7 PMID:9621055,PMID:24903568,PMID:25405808,PMID:9129070,PMID:8627655 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 700 T A ganciclovir susceptible 0.9 PMID:9621055,PMID:24903568,PMID:25405808,PMID:9129070,PMID:8627655 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 700 T A cidofovir susceptible 1.5 PMID:9621055,PMID:24903568,PMID:25405808,PMID:9129070,PMID:8627655 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 700 T A foscarnet intermediate 4.7 PMID:9621055,PMID:24903568,PMID:25405808,PMID:9129070,PMID:8627655 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 700 T A ganciclovir susceptible 0.9 PMID:9621055,PMID:24903568,PMID:25405808,PMID:9129070,PMID:8627655 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 715 V A cidofovir susceptible 0.47 PMID:27058773 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 715 V A foscarnet low-level resistance 2.5 PMID:27058773 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 715 V A ganciclovir susceptible 1.77 PMID:27058773 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL54 X17403.1 715 V M cidofovir susceptible 1.1 PMID:8627655,PMID:24903568,PMID:12198609,PMID:23375740,PMID:23668613,PMID:26098499,PMID:9621055,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 715 V M foscarnet high-level resistance 5.5 PMID:8627655,PMID:24903568,PMID:12198609,PMID:23375740,PMID:23668613,PMID:26098499,PMID:9621055,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 715 V M ganciclovir susceptible 1 PMID:8627655,PMID:24903568,PMID:12198609,PMID:23375740,PMID:23668613,PMID:26098499,PMID:9621055,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 715 V M cidofovir susceptible 1.1 PMID:8627655,PMID:24903568,PMID:12198609,PMID:23375740,PMID:23668613,PMID:26098499,PMID:9621055,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 715 V M foscarnet high-level resistance 5.5 PMID:8627655,PMID:24903568,PMID:12198609,PMID:23375740,PMID:23668613,PMID:26098499,PMID:9621055,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 715 V M ganciclovir susceptible 1 PMID:8627655,PMID:24903568,PMID:12198609,PMID:23375740,PMID:23668613,PMID:26098499,PMID:9621055,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 722 I V brincidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 722 I V cidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 722 I V cyclopropavir sensitive CHARMD Observation: Natural polymorphism @@ -1133,12 +1133,12 @@ HCMVUL54 X17403.1 737 L M foscarnet sensitive CHARMD Observation: Natural poly HCMVUL54 X17403.1 737 L M ganciclovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 737 L M letermovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 737 L M maribavir sensitive CHARMD Observation: Natural polymorphism -HCMVUL54 X17403.1 756 E D cidofovir susceptible 0.7 PMID:12825168,PMID:24903568,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 756 E D foscarnet intermediate 3.4 PMID:12825168,PMID:24903568,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 756 E D ganciclovir susceptible 1.2 PMID:12825168,PMID:24903568,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 756 E K cidofovir low-level resistance 2.2 PMID:12825168,PMID:25143583,PMID:24621186,PMID:11595579 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 756 E K foscarnet high-level resistance 8 PMID:12825168,PMID:25143583,PMID:24621186,PMID:11595579 CHARMD Fold IC50 values: 8, >8; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 756 E K ganciclovir low-level resistance 2.5 PMID:12825168,PMID:25143583,PMID:24621186,PMID:11595579 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 756 E D cidofovir susceptible 0.7 PMID:12825168,PMID:24903568,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 756 E D foscarnet intermediate 3.4 PMID:12825168,PMID:24903568,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 756 E D ganciclovir susceptible 1.2 PMID:12825168,PMID:24903568,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 756 E K cidofovir low-level resistance 2.2 PMID:12825168,PMID:25143583,PMID:24621186,PMID:11595579 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 756 E K foscarnet high-level resistance 8 PMID:12825168,PMID:25143583,PMID:24621186,PMID:11595579 CHARMD Fold IC50 values: 8, >8; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 756 E K ganciclovir low-level resistance 2.5 PMID:12825168,PMID:25143583,PMID:24621186,PMID:11595579 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 756 E Q cidofovir susceptible 1 PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 756 E Q foscarnet intermediate 4.3 PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 756 E Q ganciclovir susceptible 1.7 PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer @@ -1152,12 +1152,12 @@ HCMVUL54 X17403.1 759 V M maribavir sensitive CHARMD Observation: Natural poly HCMVUL54 X17403.1 773 L V cidofovir low-level resistance 2.5 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 773 L V foscarnet intermediate 4.4 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 773 L V ganciclovir intermediate 3 PMID:24890586 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 776 L M cidofovir susceptible 1 PMID:18419454,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 776 L M foscarnet intermediate 3.5 PMID:18419454,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 776 L M ganciclovir low-level resistance 2.5 PMID:18419454,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 781 V I cidofovir susceptible 1.2 PMID:9621055,PMID:11595579,PMID:11704031,PMID:9207351,PMID:24890586,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells IS50 =1 ? 5 -HCMVUL54 X17403.1 781 V I foscarnet high-level resistance 5.2 PMID:9621055,PMID:11595579,PMID:11704031,PMID:9207351,PMID:24890586,PMID:12599051 CHARMD Fold IC50 values: 5.2, 4-5.2; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells IS50 =1 ? 6 -HCMVUL54 X17403.1 781 V I ganciclovir intermediate 4 PMID:9621055,PMID:11595579,PMID:11704031,PMID:9207351,PMID:24890586,PMID:12599051 CHARMD Fold IC50 values: 4, 1-4; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells IS50 =1 ? 4 +HCMVUL54 X17403.1 776 L M cidofovir susceptible 1 PMID:18419454,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 776 L M foscarnet intermediate 3.5 PMID:18419454,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 776 L M ganciclovir low-level resistance 2.5 PMID:18419454,PMID:24903568 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 781 V I cidofovir susceptible 1.2 PMID:9621055,PMID:11595579,PMID:11704031,PMID:9207351,PMID:24890586,PMID:12599051 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells IS50 =1 ? 5 +HCMVUL54 X17403.1 781 V I foscarnet high-level resistance 5.2 PMID:9621055,PMID:11595579,PMID:11704031,PMID:9207351,PMID:24890586,PMID:12599051 CHARMD Fold IC50 values: 5.2, 4-5.2; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells IS50 =1 ? 6 +HCMVUL54 X17403.1 781 V I ganciclovir intermediate 4 PMID:9621055,PMID:11595579,PMID:11704031,PMID:9207351,PMID:24890586,PMID:12599051 CHARMD Fold IC50 values: 4, 1-4; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells IS50 =1 ? 4 HCMVUL54 X17403.1 783 Q R cidofovir susceptible 0.9 PMID:27940027 CHARMD Fold IC50 values: 0.9, 0.9; mean displayed | Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 783 Q R foscarnet susceptible 1.7 PMID:27940027 CHARMD Fold IC50 values: 1.7, 1.7; mean displayed | Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 783 Q R ganciclovir susceptible 1.55 PMID:27940027 CHARMD Fold IC50 values: 1.8, 1.3; mean displayed | Source origin: Laboratory strain, Clinical Isolate @@ -1177,9 +1177,9 @@ HCMVUL54 X17403.1 787 V A ganciclovir low-level resistance 2.5 PMID:23668613 CHA HCMVUL54 X17403.1 787 V E cidofovir low-level resistance 2.9 PMID:31199457 CHARMD Source origin: Clincial isolate | Assay details: Gaussia Luciferase Reporter-Based Assay HCMVUL54 X17403.1 787 V E foscarnet intermediate 3.4 PMID:31199457 CHARMD Source origin: Clincial isolate | Assay details: Gaussia Luciferase Reporter-Based Assay HCMVUL54 X17403.1 787 V E ganciclovir high-level resistance 8.6 PMID:31199457 CHARMD Source origin: Clincial isolate | Assay details: Gaussia Luciferase Reporter-Based Assay -HCMVUL54 X17403.1 787 V L cidofovir susceptible 1 PMID:12599051,PMID:21709106,PMID:11704032 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 787 V L foscarnet intermediate 4.1 PMID:12599051,PMID:21709106,PMID:11704033 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 787 V L ganciclovir low-level resistance 2.4 PMID:12599051,PMID:21709106,PMID:11704031 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 787 V L cidofovir susceptible 1 PMID:12599051,PMID:21709106,PMID:11704032 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 787 V L foscarnet intermediate 4.1 PMID:12599051,PMID:21709106,PMID:11704033 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 787 V L ganciclovir low-level resistance 2.4 PMID:12599051,PMID:21709106,PMID:11704031 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 792 R S brincidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 792 R S cidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 792 R S cyclopropavir sensitive CHARMD Observation: Natural polymorphism @@ -1206,28 +1206,28 @@ HCMVUL54 X17403.1 800 R C foscarnet sensitive PMID:24273181 CHARMD Observation: HCMVUL54 X17403.1 800 R C ganciclovir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure HCMVUL54 X17403.1 800 R C letermovir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure HCMVUL54 X17403.1 800 R C maribavir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure -HCMVUL54 X17403.1 802 L M cidofovir susceptible 1.8 PMID:9291334,PMID:11595579,PMID:11050017,PMID:23985916,PMID:20961907,PMID:15634973,PMID:9207351,PMID:9621055,PMID:21709106 CHARMD Fold IC50 values: 1.8, 0.9-1.8; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells IS50 = 1.1-3.6 -HCMVUL54 X17403.1 802 L M foscarnet high-level resistance 10.8 PMID:9291334,PMID:11595579,PMID:11050017,PMID:23985916,PMID:20961907,PMID:15634973,PMID:9207351,PMID:9621055,PMID:21709106 CHARMD Fold IC50 values: 10.8, 3.2-10.8; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells IS50 = 1.1-3.7 -HCMVUL54 X17403.1 802 L M ganciclovir intermediate 3.5 PMID:9291334,PMID:11595579,PMID:11050017,PMID:23985916,PMID:20961907,PMID:15634973,PMID:9207351,PMID:9621055,PMID:21709106 CHARMD Fold IC50 values: 3.5, 1.1-3.5; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells IS50 = 1.1-3.5 -HCMVUL54 X17403.1 802 L V cidofovir susceptible 1.1 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 802 L V foscarnet susceptible 0.9 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 802 L V ganciclovir susceptible 1.8 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 805 K Q cidofovir low-level resistance 2.2 PMID:9621055,PMID:9207351,PMID:20587852 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 805 K Q foscarnet susceptible 0.18 PMID:9621055,PMID:9207351,PMID:20587853 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 805 K Q ganciclovir susceptible 1 PMID:9621055,PMID:9207351,PMID:20587851 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 809 A V cidofovir susceptible 1.7 PMID:24890586,PMID:17709468,PMID:12198609 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 809 A V foscarnet intermediate 4.76667 PMID:24890586,PMID:17709468,PMID:12198609,PMID:27940027 CHARMD Fold IC50 values: 6.3, 3.6, 4.4; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate -HCMVUL54 X17403.1 809 A V ganciclovir low-level resistance 2.6 PMID:24890586,PMID:17709468,PMID:12198609 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 802 L M cidofovir susceptible 1.8 PMID:9291334,PMID:11595579,PMID:11050017,PMID:23985916,PMID:20961907,PMID:15634973,PMID:9207351,PMID:9621055,PMID:21709106 CHARMD Fold IC50 values: 1.8, 0.9-1.8; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells IS50 = 1.1-3.6 +HCMVUL54 X17403.1 802 L M foscarnet high-level resistance 10.8 PMID:9291334,PMID:11595579,PMID:11050017,PMID:23985916,PMID:20961907,PMID:15634973,PMID:9207351,PMID:9621055,PMID:21709106 CHARMD Fold IC50 values: 10.8, 3.2-10.8; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells IS50 = 1.1-3.7 +HCMVUL54 X17403.1 802 L M ganciclovir intermediate 3.5 PMID:9291334,PMID:11595579,PMID:11050017,PMID:23985916,PMID:20961907,PMID:15634973,PMID:9207351,PMID:9621055,PMID:21709106 CHARMD Fold IC50 values: 3.5, 1.1-3.5; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells IS50 = 1.1-3.5 +HCMVUL54 X17403.1 802 L V cidofovir susceptible 1.1 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 802 L V foscarnet susceptible 0.9 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 802 L V ganciclovir susceptible 1.8 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 805 K Q cidofovir low-level resistance 2.2 PMID:9621055,PMID:9207351,PMID:20587852 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 805 K Q foscarnet susceptible 0.18 PMID:9621055,PMID:9207351,PMID:20587853 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 805 K Q ganciclovir susceptible 1 PMID:9621055,PMID:9207351,PMID:20587851 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 809 A V cidofovir susceptible 1.7 PMID:24890586,PMID:17709468,PMID:12198609 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 809 A V foscarnet intermediate 4.76667 PMID:24890586,PMID:17709468,PMID:12198609,PMID:27940027 CHARMD Fold IC50 values: 6.3, 3.6, 4.4; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate +HCMVUL54 X17403.1 809 A V ganciclovir low-level resistance 2.6 PMID:24890586,PMID:17709468,PMID:12198609 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 812 V L brincidofovir low-level resistance 2.4 PMID:27044553 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant -HCMVUL54 X17403.1 812 V L cidofovir intermediate 3.2 PMID:9721246,PMID:15634973,PMID:21709106 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 812 V L foscarnet low-level resistance 2.9 PMID:9721246,PMID:15634973,PMID:21709106 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 812 V L ganciclovir low-level resistance 2.5 PMID:9721246,PMID:15634973,PMID:21709106 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 812 V L cidofovir intermediate 3.2 PMID:9721246,PMID:15634973,PMID:21709106 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 812 V L foscarnet low-level resistance 2.9 PMID:9721246,PMID:15634973,PMID:21709106 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 812 V L ganciclovir low-level resistance 2.5 PMID:9721246,PMID:15634973,PMID:21709106 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 813 T S cidofovir low-level resistance 2.9 PMID:17709468 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 813 T S foscarnet intermediate 4.9 PMID:17709468 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 813 T S ganciclovir low-level resistance 2.5 PMID:17709468 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL54 X17403.1 821 T I cidofovir susceptible 1.9 PMID:9621055,PMID:9207351,PMID:20587852 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 821 T I foscarnet high-level resistance 21 PMID:9621055,PMID:9207351,PMID:20587853 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 821 T I ganciclovir intermediate 4.5 PMID:9621055,PMID:9207351,PMID:20587851 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 821 T I cidofovir susceptible 1.9 PMID:9621055,PMID:9207351,PMID:20587852 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 821 T I foscarnet high-level resistance 21 PMID:9621055,PMID:9207351,PMID:20587853 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 821 T I ganciclovir intermediate 4.5 PMID:9621055,PMID:9207351,PMID:20587851 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 823 V A cidofovir intermediate 3.6 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 823 V A foscarnet susceptible 0.5 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 823 V A ganciclovir low-level resistance 2.4 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate @@ -1235,18 +1235,18 @@ HCMVUL54 X17403.1 827 M I brincidofovir susceptible 0.8 PMID:26941282 CHARMD Sou HCMVUL54 X17403.1 827 M I cidofovir susceptible 0.7 PMID:26941282 CHARMD Source origin: Clinical Isolate | Assay details: marker transfer | Observation: Natural polymorphism HCMVUL54 X17403.1 827 M I foscarnet sensitive PMID:26941282 CHARMD Source origin: Clinical Isolate | Assay details: marker transfer | Observation: Natural polymorphism HCMVUL54 X17403.1 827 M I ganciclovir sensitive PMID:26941282 CHARMD Source origin: Clinical Isolate | Assay details: marker transfer | Observation: Natural polymorphism -HCMVUL54 X17403.1 829 P S cidofovir susceptible 1.6 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 829 P S foscarnet susceptible 1.1 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 829 P S ganciclovir low-level resistance 2 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 834 A P cidofovir intermediate 3 PMID:15258973,PMID:23985916,PMID:20961907,PMID:26098499,PMID:24183928,PMID:17043128 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 834 A P foscarnet high-level resistance 6.4 PMID:15258973,PMID:23985916,PMID:20961907,PMID:26098499,PMID:24183928,PMID:17043128 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 834 A P ganciclovir high-level resistance 5.4 PMID:15258973,PMID:23985916,PMID:20961907,PMID:26098499,PMID:24183928,PMID:17043128 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 829 P S cidofovir susceptible 1.6 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 829 P S foscarnet susceptible 1.1 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 829 P S ganciclovir low-level resistance 2 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 834 A P cidofovir intermediate 3 PMID:15258973,PMID:23985916,PMID:20961907,PMID:26098499,PMID:24183928,PMID:17043128 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 834 A P foscarnet high-level resistance 6.4 PMID:15258973,PMID:23985916,PMID:20961907,PMID:26098499,PMID:24183928,PMID:17043128 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 834 A P ganciclovir high-level resistance 5.4 PMID:15258973,PMID:23985916,PMID:20961907,PMID:26098499,PMID:24183928,PMID:17043128 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 838 T A cidofovir susceptible 0.8 PMID:15634973 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 838 T A foscarnet low-level resistance 2.4 PMID:15634973 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL54 X17403.1 838 T A ganciclovir susceptible 1.8 PMID:15634973 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 841 G A cidofovir low-level resistance 2.6 PMID:17709468,PMID:23985916,PMID:9129071 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 841 G A foscarnet intermediate 4.3 PMID:17709468,PMID:23985916,PMID:9129072 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 841 G A ganciclovir intermediate 3.2 PMID:17709468,PMID:23985916,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 841 G A cidofovir low-level resistance 2.6 PMID:17709468,PMID:23985916,PMID:9129071 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 841 G A foscarnet intermediate 4.3 PMID:17709468,PMID:23985916,PMID:9129072 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 841 G A ganciclovir intermediate 3.2 PMID:17709468,PMID:23985916,PMID:9129070 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 841 G S cidofovir susceptible 1.1 PMID:24273181 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 841 G S foscarnet low-level resistance 2.1 PMID:24273181 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 841 G S ganciclovir low-level resistance 2.2 PMID:24273181 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer @@ -1273,9 +1273,9 @@ HCMVUL54 X17403.1 855 N D maribavir sensitive PMID:24273181 CHARMD Observation: HCMVUL54 X17403.1 859 P A cidofovir susceptible 1 PMID:24273181 CHARMD Marker transfer: Recombinant HCMVUL54 X17403.1 859 P A foscarnet susceptible 0.8 PMID:24273181 CHARMD Marker transfer: Recombinant HCMVUL54 X17403.1 859 P A ganciclovir susceptible 0.8 PMID:24273181 CHARMD Marker transfer: Recombinant -HCMVUL54 X17403.1 862 L F cidofovir susceptible 0.9 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 862 L F foscarnet susceptible 1.1 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 862 L F ganciclovir susceptible 1.7 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 862 L F cidofovir susceptible 0.9 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 862 L F foscarnet susceptible 1.1 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 862 L F ganciclovir susceptible 1.7 PMID:21709106,PMID:22001948 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 863 H R brincidofovir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure HCMVUL54 X17403.1 863 H R cidofovir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure HCMVUL54 X17403.1 863 H R cyclopropavir sensitive PMID:24273181 CHARMD Observation: Victor trial , before any exposure @@ -1411,9 +1411,9 @@ HCMVUL54 X17403.1 932 S N foscarnet sensitive CHARMD Observation: Natural poly HCMVUL54 X17403.1 932 S N ganciclovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 932 S N letermovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 932 S N maribavir sensitive CHARMD Observation: Natural polymorphism -HCMVUL54 X17403.1 946 V L cidofovir susceptible 0.9 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 946 V L foscarnet low-level resistance 2.4 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 946 V L ganciclovir susceptible 1.1 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 946 V L cidofovir susceptible 0.9 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 946 V L foscarnet low-level resistance 2.4 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 946 V L ganciclovir susceptible 1.1 PMID:21709106,PMID:22001948 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 947 K E cidofovir susceptible 1 PMID:24273181 CHARMD Marker transfer: Recombinant HCMVUL54 X17403.1 947 K E foscarnet susceptible 1.1 PMID:24273181 CHARMD Marker transfer: Recombinant HCMVUL54 X17403.1 947 K E ganciclovir susceptible 1 PMID:24273181 CHARMD Marker transfer: Recombinant @@ -1447,9 +1447,9 @@ HCMVUL54 X17403.1 956 S Y foscarnet sensitive CHARMD Observation: Natural poly HCMVUL54 X17403.1 956 S Y ganciclovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 956 S Y letermovir sensitive CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 956 S Y maribavir sensitive CHARMD Observation: Natural polymorphism -HCMVUL54 X17403.1 957 L F cidofovir susceptible 1.4 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 957 L F foscarnet susceptible 1.3 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 957 L F ganciclovir low-level resistance 2.7 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 957 L F cidofovir susceptible 1.4 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 957 L F foscarnet susceptible 1.3 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 957 L F ganciclovir low-level resistance 2.7 PMID:21709106,PMID:22001948 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 959 M T cidofovir susceptible 0.9 PMID:24273181 CHARMD Marker transfer: Recombinant HCMVUL54 X17403.1 959 M T foscarnet susceptible 1.2 PMID:24273181 CHARMD Marker transfer: Recombinant HCMVUL54 X17403.1 959 M T ganciclovir susceptible 1.2 PMID:24273181 CHARMD Marker transfer: Recombinant @@ -1460,12 +1460,12 @@ HCMVUL54 X17403.1 972 A V foscarnet sensitive PMID:24273181 CHARMD Observation: HCMVUL54 X17403.1 972 A V ganciclovir sensitive PMID:24273181 CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 972 A V letermovir sensitive PMID:24273181 CHARMD Observation: Natural polymorphism HCMVUL54 X17403.1 972 A V maribavir sensitive PMID:24273181 CHARMD Observation: Natural polymorphism -HCMVUL54 X17403.1 981 D D981del cidofovir low-level resistance 2.8 PMID:11069251,PMID:15980340,PMID:12825168,PMID:24890586 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 981 D D981del foscarnet intermediate 3.6 PMID:11069251,PMID:15980340,PMID:12825168,PMID:24890586 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 981 D D981del ganciclovir high-level resistance 8.3 PMID:11069251,PMID:15980340,PMID:12825168,PMID:24890586 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL54 X17403.1 987 A G cidofovir high-level resistance 8.26667 PMID:9621055,PMID:12198609,PMID:23985916,PMID:15258973,PMID:20961907,PMID:11704031,PMID:27940027 CHARMD Fold IC50 values: 11.3, 8.5, 5; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : | Source origin: Laboratory strain, Clinical Isolate -HCMVUL54 X17403.1 987 A G foscarnet susceptible 1.2 PMID:9621055,PMID:12198609,PMID:23985916,PMID:15258973,PMID:20961907,PMID:11704031 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL54 X17403.1 987 A G ganciclovir high-level resistance 5.3 PMID:9621055,PMID:12198609,PMID:23985916,PMID:15258973,PMID:20961907,PMID:11704031 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL54 X17403.1 981 D D981del cidofovir low-level resistance 2.8 PMID:11069251,PMID:15980340,PMID:12825168,PMID:24890586 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 981 D D981del foscarnet intermediate 3.6 PMID:11069251,PMID:15980340,PMID:12825168,PMID:24890586 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 981 D D981del ganciclovir high-level resistance 8.3 PMID:11069251,PMID:15980340,PMID:12825168,PMID:24890586 CHARMD Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL54 X17403.1 987 A G cidofovir high-level resistance 8.26667 PMID:9621055,PMID:12198609,PMID:23985916,PMID:15258973,PMID:20961907,PMID:11704031,PMID:27940027 CHARMD Fold IC50 values: 11.3, 8.5, 5; mean displayed | Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Source origin: Laboratory strain, Clinical Isolate +HCMVUL54 X17403.1 987 A G foscarnet susceptible 1.2 PMID:9621055,PMID:12198609,PMID:23985916,PMID:15258973,PMID:20961907,PMID:11704031 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL54 X17403.1 987 A G ganciclovir high-level resistance 5.3 PMID:9621055,PMID:12198609,PMID:23985916,PMID:15258973,PMID:20961907,PMID:11704031 CHARMD Source origin: Clincial isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL54 X17403.1 987 A V cidofovir susceptible 0.9 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 987 A V foscarnet intermediate 3.1 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL54 X17403.1 987 A V ganciclovir susceptible 0.9 PMID:32726419 CHARMD Source origin: Laboratory strain, Clinical Isolate @@ -1753,18 +1753,18 @@ HCMVUL56 X17403.1 221 A V foscarnet sensitive PMID:25194992 CHARMD Source origi HCMVUL56 X17403.1 221 A V ganciclovir sensitive PMID:25194992 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 221 A V letermovir sensitive PMID:25194992 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 221 A V maribavir sensitive PMID:25194992 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism -HCMVUL56 X17403.1 229 S F letermovir susceptible 1.8 PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : +HCMVUL56 X17403.1 229 S F letermovir susceptible 1.8 PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP HCMVUL56 X17403.1 229 S Y letermovir low-level resistance 2 PMID:38880196 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 231 V A letermovir low-level resistance 2.1 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 231 V L letermovir high-level resistance 7.33333 PMID:24189264,PMID:26259791,PMID:29107686,PMID:29914965,PMID:31940472,PMID:36170912,PMID:38880196 CHARMD Fold IC50 values: 5, 8.9, 8.1; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluorescence | Observation: Other publication ID : | Source origin: Laboratory strain, Clinical Isolate -HCMVUL56 X17403.1 232 N Y letermovir high-level resistance 17 PMID:28827420,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : +HCMVUL56 X17403.1 231 V A letermovir low-level resistance 2.1 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 231 V L letermovir high-level resistance 7.33333 PMID:24189264,PMID:26259791,PMID:29107686,PMID:29914965,PMID:31940472,PMID:36170912,PMID:38880196 CHARMD Fold IC50 values: 5, 8.9, 8.1; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluorescence | Source origin: Laboratory strain, Clinical Isolate +HCMVUL56 X17403.1 232 N Y letermovir high-level resistance 17 PMID:28827420,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP HCMVUL56 X17403.1 234 Q R letermovir low-level resistance 2 PMID:36170912 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 236 V A letermovir low-level resistance 2.9 PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 236 V L letermovir high-level resistance 14 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 236 V M letermovir high-level resistance 45 PMID:24189264,PMID:29107686,PMID:29914965,PMID:26113373,PMID:28807919,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluoresence, Gluc | Observation: Other publication ID : +HCMVUL56 X17403.1 236 V A letermovir low-level resistance 2.9 PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 236 V L letermovir high-level resistance 14 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 236 V M letermovir high-level resistance 45 PMID:24189264,PMID:29107686,PMID:29914965,PMID:26113373,PMID:28807919,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluoresence, Gluc HCMVUL56 X17403.1 236 V M maribavir susceptible 0.12 PMID:30040968 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluoresence, Gluc -HCMVUL56 X17403.1 237 E D letermovir high-level resistance 10 PMID:26259791,PMID:28827420 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 241 L P letermovir high-level resistance 218 PMID:24189264,PMID:26259791,PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluorescence | Observation: Other publication ID : +HCMVUL56 X17403.1 237 E D letermovir high-level resistance 10 PMID:26259791,PMID:28827420 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 241 L P letermovir high-level resistance 218 PMID:24189264,PMID:26259791,PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluorescence HCMVUL56 X17403.1 242 D G brincidofovir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 242 D G cidofovir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 242 D G cyclopropavir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism @@ -1773,19 +1773,19 @@ HCMVUL56 X17403.1 242 D G ganciclovir sensitive PMID:18771048 CHARMD Source ori HCMVUL56 X17403.1 242 D G letermovir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 242 D G maribavir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 243 L P letermovir susceptible 1 PMID:36170912 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 244 T K letermovir intermediate 3.3 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 254 L F letermovir intermediate 3.2 PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 257 L F letermovir high-level resistance 8.6 PMID:29107686,PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 257 L I letermovir intermediate 4.9 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 258 K E letermovir high-level resistance 14 PMID:28827420,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 261 F C letermovir intermediate 4.4 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 261 F L letermovir low-level resistance 2.8 PMID:26259791,PMID:28827420,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : +HCMVUL56 X17403.1 244 T K letermovir intermediate 3.3 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 254 L F letermovir intermediate 3.2 PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 257 L F letermovir high-level resistance 8.6 PMID:29107686,PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 257 L I letermovir intermediate 4.9 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 258 K E letermovir high-level resistance 14 PMID:28827420,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 261 F C letermovir intermediate 4.4 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 261 F L letermovir low-level resistance 2.8 PMID:26259791,PMID:28827420,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP HCMVUL56 X17403.1 262 S C letermovir susceptible 1 PMID:36170912 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 321 Y C letermovir intermediate 4.6 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 325 C F letermovir high-level resistance 3000 PMID:26259791,PMID:30642941,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 325 C R letermovir high-level resistance 3000 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 325 C W letermovir high-level resistance 9300 PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 325 C Y letermovir high-level resistance 8796 PMID:24189264,PMID:26259791,PMID:29914965,PMID:30286286,PMID:30642941,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluorescence | Observation: Other publication ID : +HCMVUL56 X17403.1 321 Y C letermovir intermediate 4.6 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 325 C F letermovir high-level resistance 3000 PMID:26259791,PMID:30642941,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 325 C R letermovir high-level resistance 3000 PMID:26259791,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 325 C W letermovir high-level resistance 9300 PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 325 C Y letermovir high-level resistance 8796 PMID:24189264,PMID:26259791,PMID:29914965,PMID:30286286,PMID:30642941,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluorescence HCMVUL56 X17403.1 327 A V brincidofovir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 327 A V cidofovir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 327 A V cyclopropavir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism @@ -1794,21 +1794,21 @@ HCMVUL56 X17403.1 327 A V ganciclovir sensitive PMID:18771048 CHARMD Source ori HCMVUL56 X17403.1 327 A V letermovir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 327 A V maribavir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 328 L I letermovir susceptible 1.4 PMID:36170912 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 328 L V letermovir susceptible 1.9 PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : +HCMVUL56 X17403.1 328 L V letermovir susceptible 1.9 PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP HCMVUL56 X17403.1 329 M I letermovir susceptible 0.77 PMID:38880196 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 329 M T letermovir intermediate 4.4 PMID:26259791,PMID:28827420,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : +HCMVUL56 X17403.1 329 M T letermovir intermediate 4.4 PMID:26259791,PMID:28827420,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP HCMVUL56 X17403.1 335 H Y letermovir susceptible 0.8 PMID:36170912 CHARMD HCMVUL56 X17403.1 339 E G letermovir susceptible 1.2 PMID:36170912 CHARMD Source origin: Clinical Isolate HCMVUL56 X17403.1 345 F L letermovir susceptible 1.03 PMID:35993155 CHARMD Fold IC50 values: 1.03, 0.95-1.03; mean displayed | Source origin: Laboratory strain, Clinical Isolate HCMVUL56 X17403.1 350 K R letermovir susceptible 1.1 PMID:36170912 CHARMD Source origin: Clinical Isolate HCMVUL56 X17403.1 363 V I letermovir intermediate 3.7 PMID:36170912 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 365 A S letermovir low-level resistance 2 PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : -HCMVUL56 X17403.1 368 N D letermovir low-level resistance 2 PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : +HCMVUL56 X17403.1 365 A S letermovir low-level resistance 2 PMID:29914965,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP +HCMVUL56 X17403.1 368 N D letermovir low-level resistance 2 PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP HCMVUL56 X17403.1 368 N I letermovir susceptible 1.3 PMID:36170912 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 369 R G letermovir high-level resistance 44 PMID:24189264,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, fluorescence | Observation: Other publication ID : +HCMVUL56 X17403.1 369 R G letermovir high-level resistance 44 PMID:24189264,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, fluorescence HCMVUL56 X17403.1 369 R K letermovir intermediate 4.9 PMID:36170912 CHARMD Source origin: Clinical Isolate -HCMVUL56 X17403.1 369 R M letermovir high-level resistance 13 PMID:24189264,PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluorescence | Observation: Other publication ID : -HCMVUL56 X17403.1 369 R S letermovir high-level resistance 48 PMID:24189264,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, fluorescence | Observation: Other publication ID : +HCMVUL56 X17403.1 369 R M letermovir high-level resistance 13 PMID:24189264,PMID:29107686,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, SEAP, fluorescence +HCMVUL56 X17403.1 369 R S letermovir high-level resistance 48 PMID:24189264,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, fluorescence HCMVUL56 X17403.1 369 R T letermovir high-level resistance 52 PMID:31781762 CHARMD Source origin: Clinical Isolate | Assay details: PRA, marker transfer | Observation: Natural polymorphism HCMVUL56 X17403.1 393 E K brincidofovir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL56 X17403.1 393 E K cidofovir sensitive PMID:18771048 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism @@ -2248,7 +2248,7 @@ HCMVUL89 X17403.1 294 N D letermovir sensitive PMID:17503664 CHARMD Source orig HCMVUL89 X17403.1 294 N D maribavir sensitive PMID:17503664 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL89 X17403.1 320 N H letermovir susceptible 1.8 PMID:28827420 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP HCMVUL89 X17403.1 329 N S letermovir low-level resistance 2 PMID:28827420 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP -HCMVUL89 X17403.1 344 D E letermovir susceptible 1.8 PMID:28827420,PMID:29107686 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : +HCMVUL89 X17403.1 344 D E letermovir susceptible 1.8 PMID:28827420,PMID:29107686 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP HCMVUL89 X17403.1 344 D E maribavir susceptible 0.09 PMID:30040968 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant HCMVUL89 X17403.1 345 S A brincidofovir sensitive PMID:17503664 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism HCMVUL89 X17403.1 345 S A cidofovir sensitive PMID:17503664 CHARMD Source origin: Clinical Isolate | Observation: Natural polymorphism @@ -2525,10 +2525,10 @@ HCMVUL97 X17403.1 345 V I ganciclovir susceptible 1.3 PMID:34273445 CHARMD Sourc HCMVUL97 X17403.1 345 V I maribavir susceptible 0.4 PMID:34273445 CHARMD Source origin: Laboratory strain, Clinical Isolate HCMVUL97 X17403.1 348 L V ganciclovir susceptible 0.9 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 348 L V maribavir susceptible 1.6 PMID:34273445 CHARMD Source origin: Clinical Isolate -HCMVUL97 X17403.1 353 V A ganciclovir susceptible 1 PMID:17538888,PMID:17942550,PMID:22664236,PMID:23650173 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP, PRA | Observation: Other publication ID : -HCMVUL97 X17403.1 353 V A maribavir high-level resistance 10 PMID:17538888,PMID:17942550,PMID:22664236,PMID:23650173,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP, PRA | Observation: Other publication ID : IS50: 5-20 according to Chou 2020 : -HCMVUL97 X17403.1 355 K K355del ganciclovir high-level resistance 16 PMID:23650173,PMID:16306620 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer, enzymatic assay, SEAP | Observation: Other publication ID : -HCMVUL97 X17403.1 355 K K355del maribavir high-level resistance 304 PMID:23650173 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: Enzymatic assay, SEAP | Observation: Other publication ID : +HCMVUL97 X17403.1 353 V A ganciclovir susceptible 1 PMID:17538888,PMID:17942550,PMID:22664236,PMID:23650173 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP, PRA +HCMVUL97 X17403.1 353 V A maribavir high-level resistance 10 PMID:17538888,PMID:17942550,PMID:22664236,PMID:23650173,PMID:31940472 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP, PRA | Observation: IS50: 5-20 according to Chou 2020 +HCMVUL97 X17403.1 355 K K355del ganciclovir high-level resistance 16 PMID:23650173,PMID:16306620 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer, enzymatic assay, SEAP +HCMVUL97 X17403.1 355 K K355del maribavir high-level resistance 304 PMID:23650173 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: Enzymatic assay, SEAP HCMVUL97 X17403.1 356 K V brincidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL97 X17403.1 356 K V cidofovir sensitive CHARMD Observation: Natural polymorphism HCMVUL97 X17403.1 356 K V cyclopropavir sensitive CHARMD Observation: Natural polymorphism @@ -2552,27 +2552,27 @@ HCMVUL97 X17403.1 356 V W foscarnet sensitive CHARMD Observation: Natural poly HCMVUL97 X17403.1 356 V W ganciclovir sensitive CHARMD Observation: Natural polymorphism HCMVUL97 X17403.1 356 V W letermovir sensitive CHARMD Observation: Natural polymorphism HCMVUL97 X17403.1 356 V W maribavir sensitive CHARMD Observation: Natural polymorphism -HCMVUL97 X17403.1 359 K E ganciclovir intermediate 4 PMID:31568799,PMID:31940472 CHARMD Source origin: Clincial isolate | Assay details: PRA, marker transfer | Observation: 50 : 2.2-4.9 according to Chou 2020 : +HCMVUL97 X17403.1 359 K E ganciclovir intermediate 4 PMID:31568799,PMID:31940472 CHARMD Source origin: Clincial isolate | Assay details: PRA, marker transfer | Observation: 50 : 2.2-4.9 according to Chou 2020 HCMVUL97 X17403.1 359 K N ganciclovir low-level resistance 2.1 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 359 K N maribavir susceptible 0.7 PMID:34273445 CHARMD Source origin: Clinical Isolate -HCMVUL97 X17403.1 359 K Q ganciclovir intermediate 4 PMID:31568799,PMID:31940472 CHARMD Source origin: Clincial isolate | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 : +HCMVUL97 X17403.1 359 K Q ganciclovir intermediate 4 PMID:31568799,PMID:31940472 CHARMD Source origin: Clincial isolate | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 HCMVUL97 X17403.1 362 E D ganciclovir intermediate 3.8 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 362 E D maribavir susceptible 0.1 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 378 A T ganciclovir susceptible 1 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 378 A T maribavir susceptible 1.1 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 388 V M ganciclovir susceptible 1.2 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 388 V M maribavir susceptible 1.1 PMID:34273445 CHARMD Source origin: Clinical Isolate -HCMVUL97 X17403.1 397 L R ganciclovir low-level resistance 2.3 PMID:38163624,PMID:16962820,PMID:17942550,PMID:17538888,PMID:12121906,PMID:15388454 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: DNA hybridization assay, PRA, SEAP | Observation: Updated 2024 Other publication ID : -HCMVUL97 X17403.1 397 L R maribavir high-level resistance 390 PMID:38163624,PMID:17942550,PMID:17538888,PMID:12121906,PMID:15388453 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: DNA hybridization assay, PRA, SEAP | Observation: Updated 2024, 16962820Other publication ID : -HCMVUL97 X17403.1 405 L P ganciclovir low-level resistance 2.7 PMID:20385869,PMID:16962820,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : , -HCMVUL97 X17403.1 409 T M ganciclovir susceptible 1.3 PMID:38163624,PMID:17538888,PMID:17942550,PMID:27667983,PMID:30329038,PMID:20504236,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP | Observation: Other publication ID :Updated 2024 , -HCMVUL97 X17403.1 409 T M maribavir high-level resistance 79 PMID:38163624,PMID:17942550,PMID:27667983,PMID:30329038,PMID:20504236,PMID:31940472,PMID:32726419 CHARMD Fold IC50 values: 80, 78; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP | Observation: Other publication ID : Updated 202417538888, IS50: 21-99 according to Chou 2020 : | Source origin: Laboratory strain, Clinical Isolate +HCMVUL97 X17403.1 397 L R ganciclovir low-level resistance 2.3 PMID:38163624,PMID:16962820,PMID:17942550,PMID:17538888,PMID:12121906,PMID:15388454 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: DNA hybridization assay, PRA, SEAP | Observation: Updated 2024 +HCMVUL97 X17403.1 397 L R maribavir high-level resistance 390 PMID:38163624,PMID:17942550,PMID:17538888,PMID:12121906,PMID:15388453 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: DNA hybridization assay, PRA, SEAP | Observation: Updated 2024 +HCMVUL97 X17403.1 405 L P ganciclovir low-level resistance 2.7 PMID:20385869,PMID:16962820,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 409 T M ganciclovir susceptible 1.3 PMID:38163624,PMID:17538888,PMID:17942550,PMID:27667983,PMID:30329038,PMID:20504236,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP | Observation: Updated 2024 +HCMVUL97 X17403.1 409 T M maribavir high-level resistance 79 PMID:38163624,PMID:17942550,PMID:27667983,PMID:30329038,PMID:20504236,PMID:31940472,PMID:32726419 CHARMD Fold IC50 values: 80, 78; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, SEAP | Observation: Updated 202417538888, IS50: 21-99 according to Chou 2020 | Source origin: Laboratory strain, Clinical Isolate HCMVUL97 X17403.1 411 H L ganciclovir susceptible 0.7 PMID:17942550 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP -HCMVUL97 X17403.1 411 H L maribavir high-level resistance 99 PMID:17942550,PMID:31940472 CHARMD Fold IC50 values: 99, 21-99; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: IS50: 21-99 according to Chou 2020 : +HCMVUL97 X17403.1 411 H L maribavir high-level resistance 99 PMID:17942550,PMID:31940472 CHARMD Fold IC50 values: 99, 21-99; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: IS50: 21-99 according to Chou 2020 HCMVUL97 X17403.1 411 H N ganciclovir susceptible 0.71 PMID:17942550 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP HCMVUL97 X17403.1 411 H N maribavir high-level resistance 9 PMID:17942550,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: IS50: 5-20 according to Chou 2020 : Assays : SEAP -HCMVUL97 X17403.1 411 H Y ganciclovir susceptible 0.5 PMID:38163624,PMID:17942550,PMID:30329038,PMID:20504236,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : updated 2024 , -HCMVUL97 X17403.1 411 H Y maribavir high-level resistance 16 PMID:38163624,PMID:17942550,PMID:30329038,PMID:20504236,PMID:31940472,PMID:32726419 CHARMD Fold IC50 values: 17, 15; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: Other publication ID : updated 2024 , IS50: 5-20 according to Chou 2020 : Assays : SEAP | Source origin: Laboratory strain, Clinical Isolate +HCMVUL97 X17403.1 411 H Y ganciclovir susceptible 0.5 PMID:38163624,PMID:17942550,PMID:30329038,PMID:20504236,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: updated 2024 +HCMVUL97 X17403.1 411 H Y maribavir high-level resistance 16 PMID:38163624,PMID:17942550,PMID:30329038,PMID:20504236,PMID:31940472,PMID:32726419 CHARMD Fold IC50 values: 17, 15; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: updated 2024 , IS50: 5-20 according to Chou 2020 : Assays : SEAP | Source origin: Laboratory strain, Clinical Isolate HCMVUL97 X17403.1 415 H Y ganciclovir susceptible 1.1 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 415 H Y maribavir susceptible 0.6 PMID:34273445 CHARMD Source origin: Clinical Isolate HCMVUL97 X17403.1 427 A V ganciclovir susceptible 0.95 PMID:16897654 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant @@ -2617,9 +2617,9 @@ HCMVUL97 X17403.1 449 Q R letermovir sensitive PMID:21570426 CHARMD Source orig HCMVUL97 X17403.1 449 Q R maribavir sensitive PMID:21570426 CHARMD Source origin: naive patient | Observation: Natural polymorphism HCMVUL97 X17403.1 456 D N ganciclovir high-level resistance 12 PMID:24145545 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer, SEAP HCMVUL97 X17403.1 456 D N maribavir high-level resistance 278 PMID:24145545 CHARMD Source origin: Laboratory strain | Marker transfer: Recombinant | Assay details: SEAP -HCMVUL97 X17403.1 460 M I cyclopropavir high-level resistance 12 PMID:21041510,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50: 5-20 according to Chou 2020 : -HCMVUL97 X17403.1 460 M I ganciclovir high-level resistance 12 PMID:38163624,PMID:9207351,PMID:19063923,PMID:24903568,PMID:11807689,PMID:26448304,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : updated 2024, , Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 460 M I maribavir susceptible 0.21 PMID:38163624,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: Hypersensitivity to MBV, updated 2024, IS50 : <2.2 according to Chou 2020 : +HCMVUL97 X17403.1 460 M I cyclopropavir high-level resistance 12 PMID:21041510,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50: 5-20 according to Chou 2020 +HCMVUL97 X17403.1 460 M I ganciclovir high-level resistance 12 PMID:38163624,PMID:9207351,PMID:19063923,PMID:24903568,PMID:11807689,PMID:26448304,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: updated 2024, , Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 460 M I maribavir susceptible 0.21 PMID:38163624,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: Hypersensitivity to MBV, updated 2024, IS50 : <2.2 according to Chou 2020 HCMVUL97 X17403.1 460 M L brincidofovir sensitive CHARMD Source origin: clinical isolate not yet confirmed by rrecombinant phenotype HCMVUL97 X17403.1 460 M L cidofovir sensitive CHARMD Source origin: clinical isolate not yet confirmed by rrecombinant phenotype HCMVUL97 X17403.1 460 M L cyclopropavir sensitive CHARMD Source origin: clinical isolate not yet confirmed by rrecombinant phenotype @@ -2627,28 +2627,28 @@ HCMVUL97 X17403.1 460 M L foscarnet sensitive CHARMD Source origin: clinical i HCMVUL97 X17403.1 460 M L ganciclovir sensitive CHARMD Source origin: clinical isolate not yet confirmed by rrecombinant phenotype HCMVUL97 X17403.1 460 M L letermovir sensitive CHARMD Source origin: clinical isolate not yet confirmed by rrecombinant phenotype HCMVUL97 X17403.1 460 M L maribavir sensitive CHARMD Source origin: clinical isolate not yet confirmed by rrecombinant phenotype -HCMVUL97 X17403.1 460 M T ganciclovir high-level resistance 9.3 PMID:20385869,PMID:24903568 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 460 M V cyclopropavir intermediate 4 PMID:21041510,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 : -HCMVUL97 X17403.1 460 M V ganciclovir high-level resistance 9.1 PMID:38163624,PMID:7814623,PMID:24903568,PMID:25405808,PMID:15230476,PMID:15135748,PMID:11807689,PMID:9207351,PMID:10443790,PMID:23985916,PMID:15634973,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : updated 2024, , Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 460 M V maribavir susceptible 0.3 PMID:38163624,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: updated 2024, IS50 : <2.2 according to Chou 2020 : -HCMVUL97 X17403.1 466 V G ganciclovir high-level resistance 11 PMID:20138805,PMID:23650173,PMID:31940472 CHARMD Source origin: Clinical Isolat | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer, SEAP | Observation: Other publication ID : -HCMVUL97 X17403.1 466 V G maribavir high-level resistance 321 PMID:23650173,PMID:31940472 CHARMD Source origin: Clinical Isolat | Marker transfer: Recombinant | Assay details: SEAP | Observation: IS50: >100 according to Chou 2020 : +HCMVUL97 X17403.1 460 M T ganciclovir high-level resistance 9.3 PMID:20385869,PMID:24903568 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 460 M V cyclopropavir intermediate 4 PMID:21041510,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 +HCMVUL97 X17403.1 460 M V ganciclovir high-level resistance 9.1 PMID:38163624,PMID:7814623,PMID:24903568,PMID:25405808,PMID:15230476,PMID:15135748,PMID:11807689,PMID:9207351,PMID:10443790,PMID:23985916,PMID:15634973,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: updated 2024, , Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 460 M V maribavir susceptible 0.3 PMID:38163624,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: updated 2024, IS50 : <2.2 according to Chou 2020 +HCMVUL97 X17403.1 466 V G ganciclovir high-level resistance 11 PMID:20138805,PMID:23650173,PMID:31940472 CHARMD Source origin: Clinical Isolat | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer, SEAP +HCMVUL97 X17403.1 466 V G maribavir high-level resistance 321 PMID:23650173,PMID:31940472 CHARMD Source origin: Clinical Isolat | Marker transfer: Recombinant | Assay details: SEAP | Observation: IS50: >100 according to Chou 2020 HCMVUL97 X17403.1 466 V M ganciclovir susceptible 1.3 PMID:20385869 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant HCMVUL97 X17403.1 466 V M maribavir CHARMD HCMVUL97 X17403.1 469 H Y ganciclovir susceptible 1 PMID:20385869 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: Natural polymorphism rec CHOU et al. 2010 HCMVUL97 X17403.1 476 R C ganciclovir PMID:16897654 CHARMD Source origin: Naive isolate, CNR data pHD G Champier HCMVUL97 X17403.1 478 A V ganciclovir susceptible 0.85 PMID:20385869 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant -HCMVUL97 X17403.1 480 C F ganciclovir low-level resistance 2.3 PMID:38163624,PMID:33475730,PMID:32726419 CHARMD Fold IC50 values: 2.3, 2.3; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: Other publication ID : updated 2024, , | Source origin: Clinical Isolate -HCMVUL97 X17403.1 480 C F maribavir high-level resistance 217 PMID:38163624,PMID:33475730,PMID:32726419 CHARMD Fold IC50 values: 210, 224; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: Other publication ID : updated 2024, , | Source origin: Clinical Isolate +HCMVUL97 X17403.1 480 C F ganciclovir low-level resistance 2.3 PMID:38163624,PMID:33475730,PMID:32726419 CHARMD Fold IC50 values: 2.3, 2.3; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: updated 2024 | Source origin: Clinical Isolate +HCMVUL97 X17403.1 480 C F maribavir high-level resistance 217 PMID:38163624,PMID:33475730,PMID:32726419 CHARMD Fold IC50 values: 210, 224; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: updated 2024 | Source origin: Clinical Isolate HCMVUL97 X17403.1 480 C R ganciclovir high-level resistance 9 PMID:24145545 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer, SEAP HCMVUL97 X17403.1 480 C R maribavir high-level resistance 243 PMID:24145545 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP HCMVUL97 X17403.1 510 N S ganciclovir susceptible 1.2 PMID:20385869 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: Natural polymorphism rec CHOU et al. 2010 -HCMVUL97 X17403.1 518 C Y ganciclovir high-level resistance 12 PMID:23668613,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 520 H Q cyclopropavir high-level resistance 20 PMID:21041510,PMID:31940472 CHARMD Fold IC50 values: 20, 5-20; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50: 5-20 according to Chou 2020 : -HCMVUL97 X17403.1 520 H Q ganciclovir high-level resistance 9.7 PMID:38163624,PMID:9129070,PMID:24903568,PMID:11807689,PMID:12198609,PMID:23985916,PMID:11740736,PMID:11704031,PMID:16000504,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: updated 2024, Other publication ID : , Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 520 H Q maribavir susceptible 0.66 PMID:38163624,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: updated 2024 IS50 : <2.2 according to Chou 2020 : -HCMVUL97 X17403.1 521 P L ganciclovir high-level resistance 17 PMID:23650173,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer, SEAP | Observation: Other publication ID : -HCMVUL97 X17403.1 521 P L maribavir high-level resistance 428 PMID:23650173,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: IS50: >100 according to Chou 2020 : +HCMVUL97 X17403.1 518 C Y ganciclovir high-level resistance 12 PMID:23668613,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 520 H Q cyclopropavir high-level resistance 20 PMID:21041510,PMID:31940472 CHARMD Fold IC50 values: 20, 5-20; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50: 5-20 according to Chou 2020 +HCMVUL97 X17403.1 520 H Q ganciclovir high-level resistance 9.7 PMID:38163624,PMID:9129070,PMID:24903568,PMID:11807689,PMID:12198609,PMID:23985916,PMID:11740736,PMID:11704031,PMID:16000504,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: updated 2024, , Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 520 H Q maribavir susceptible 0.66 PMID:38163624,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: updated 2024 IS50 : <2.2 according to Chou 2020 +HCMVUL97 X17403.1 521 P L ganciclovir high-level resistance 17 PMID:23650173,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer, SEAP +HCMVUL97 X17403.1 521 P L maribavir high-level resistance 428 PMID:23650173,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: SEAP | Observation: IS50: >100 according to Chou 2020 HCMVUL97 X17403.1 550 M I ganciclovir susceptible 0.85 PMID:16897654 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: Analysis of resistance in the randomized trial of valganciclovir prophylaxis for 100 days versus GCV iv HCMVUL97 X17403.1 561 G A brincidofovir sensitive PMID:20930070 CHARMD Source origin: Davis | Assay details: VGI, ND | Observation: Natural polymorphism HCMVUL97 X17403.1 561 G A cidofovir sensitive PMID:20930070 CHARMD Source origin: Davis | Assay details: VGI, ND | Observation: Natural polymorphism @@ -2668,60 +2668,60 @@ HCMVUL97 X17403.1 587 H Y maribavir sensitive PMID:20385869 CHARMD Source origi HCMVUL97 X17403.1 588 A V ganciclovir susceptible 1.15 PMID:20385869 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant HCMVUL97 X17403.1 590 A AACRALENGKL590del ganciclovir high-level resistance 6.3 PMID:11158760 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL97 X17403.1 590 A AACRALENGKLTHC590del ganciclovir PMID:10421408 CHARMD Source origin: Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: resistance-associated mutation Resistance au GCV non disponible -HCMVUL97 X17403.1 591 A ACRA591del ganciclovir high-level resistance 6 PMID:1326083,PMID:24903568,PMID:11807689,PMID:11740736,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL97 X17403.1 591 A ACRA591del ganciclovir high-level resistance 6 PMID:1326083,PMID:24903568,PMID:11807689,PMID:11740736,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL97 X17403.1 591 A D ganciclovir CHARMD Source origin: Clinical isolate | Observation: Resistance au GCV non disponible -HCMVUL97 X17403.1 591 A V ganciclovir susceptible 1.3 PMID:11050017,PMID:24184129,PMID:11807689,PMID:23375740,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 591 A V ganciclovir susceptible 1.3 PMID:11050017,PMID:24184129,PMID:11807689,PMID:23375740,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL97 X17403.1 592 C F ganciclovir high-level resistance 31.5 PMID:11505446 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL97 X17403.1 592 C G cyclopropavir intermediate 4.9 PMID:31940472 CHARMD Fold IC50 values: 4.9, 2.2-4.9; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 : -HCMVUL97 X17403.1 592 C G ganciclovir intermediate 3.1 PMID:38163624,PMID:9129070,PMID:19063923,PMID:24903568,PMID:25405808,PMID:11807689,PMID:20385869,PMID:9207351,PMID:11595579,PMID:23985916,PMID:20138805,PMID:15980340,PMID:11704031,PMID:15634973,PMID:23375740,PMID:9291334,PMID:17709468,PMID:31940472,PMID:27940027,PMID:32726419 CHARMD Fold IC50 values: 3.2, 3, 3.1, 3.1; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : , Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate -HCMVUL97 X17403.1 592 C G maribavir susceptible 0.78 PMID:38163624,PMID:19063923,PMID:24903568,PMID:25405808,PMID:11807689,PMID:20385869,PMID:9207351,PMID:11595579,PMID:23985916,PMID:20138805,PMID:15980340,PMID:11704031,PMID:15634973,PMID:23375740,PMID:9291334,PMID:17709468,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 594 A E ganciclovir intermediate 3 PMID:11807689,PMID:20385869,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 594 A G ganciclovir high-level resistance 13.5 PMID:9300382,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 594 A P ganciclovir high-level resistance 7.9 PMID:38163624,PMID:19063923,PMID:24903568,PMID:12198609,PMID:20961907,PMID:23668613,PMID:11750939 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells. -HCMVUL97 X17403.1 594 A P maribavir susceptible 1.6 PMID:38163624,PMID:19063923,PMID:24903568,PMID:12198609,PMID:20961907,PMID:23668613,PMID:11750939 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells. -HCMVUL97 X17403.1 594 A S ganciclovir intermediate 4.9 PMID:31940472 CHARMD Fold IC50 values: 4.9, 2.2-4.9; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 : -HCMVUL97 X17403.1 594 A T ganciclovir high-level resistance 5 PMID:9129070,PMID:19063923,PMID:15230476,PMID:11807689,PMID:9207351,PMID:10443790,PMID:11740736,PMID:11704031,PMID:23375740 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : update 2024 , Mutation update 2024 , frequently observed in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 594 A T maribavir susceptible 0.73 PMID:9129070,PMID:19063923,PMID:15230476,PMID:11807689,PMID:9207351,PMID:10443790,PMID:11740736,PMID:11704031,PMID:23375740 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 594 A V cyclopropavir intermediate 4.9 PMID:31940472 CHARMD Fold IC50 values: 4.9, 2.2-4.9; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 : -HCMVUL97 X17403.1 594 A V ganciclovir high-level resistance 6.9 PMID:38163624,PMID:7814623,PMID:19063923,PMID:24991428,PMID:24903568,PMID:15230476,PMID:11807689,PMID:20385869,PMID:9207351,PMID:10443790,PMID:11050017,PMID:23985916,PMID:15258973,PMID:15980340,PMID:9129070,PMID:10968438,PMID:15634973,PMID:23375740,PMID:23668613,PMID:26098499,PMID:25130511,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : update 2024 , Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 594 A V maribavir susceptible 1.9 PMID:38163624,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: Update 2024 IS50 : <2.2 according to Chou 2020 : -HCMVUL97 X17403.1 595 L F ganciclovir high-level resistance 6.2 PMID:38163624,PMID:7814623,PMID:24903568,PMID:11807689,PMID:9207351,PMID:26448304,PMID:20138805,PMID:20961907,PMID:11069251,PMID:25143583,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : update 2024 , Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 592 C G cyclopropavir intermediate 4.9 PMID:31940472 CHARMD Fold IC50 values: 4.9, 2.2-4.9; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 +HCMVUL97 X17403.1 592 C G ganciclovir intermediate 3.1 PMID:38163624,PMID:9129070,PMID:19063923,PMID:24903568,PMID:25405808,PMID:11807689,PMID:20385869,PMID:9207351,PMID:11595579,PMID:23985916,PMID:20138805,PMID:15980340,PMID:11704031,PMID:15634973,PMID:23375740,PMID:9291334,PMID:17709468,PMID:31940472,PMID:27940027,PMID:32726419 CHARMD Fold IC50 values: 3.2, 3, 3.1, 3.1; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells | Source origin: Clinical Isolate +HCMVUL97 X17403.1 592 C G maribavir susceptible 0.78 PMID:38163624,PMID:19063923,PMID:24903568,PMID:25405808,PMID:11807689,PMID:20385869,PMID:9207351,PMID:11595579,PMID:23985916,PMID:20138805,PMID:15980340,PMID:11704031,PMID:15634973,PMID:23375740,PMID:9291334,PMID:17709468,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 594 A E ganciclovir intermediate 3 PMID:11807689,PMID:20385869,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 594 A G ganciclovir high-level resistance 13.5 PMID:9300382,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 594 A P ganciclovir high-level resistance 7.9 PMID:38163624,PMID:19063923,PMID:24903568,PMID:12198609,PMID:20961907,PMID:23668613,PMID:11750939 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells. +HCMVUL97 X17403.1 594 A P maribavir susceptible 1.6 PMID:38163624,PMID:19063923,PMID:24903568,PMID:12198609,PMID:20961907,PMID:23668613,PMID:11750939 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells. +HCMVUL97 X17403.1 594 A S ganciclovir intermediate 4.9 PMID:31940472 CHARMD Fold IC50 values: 4.9, 2.2-4.9; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 +HCMVUL97 X17403.1 594 A T ganciclovir high-level resistance 5 PMID:9129070,PMID:19063923,PMID:15230476,PMID:11807689,PMID:9207351,PMID:10443790,PMID:11740736,PMID:11704031,PMID:23375740 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: update 2024 , Mutation update 2024 , frequently observed in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 594 A T maribavir susceptible 0.73 PMID:9129070,PMID:19063923,PMID:15230476,PMID:11807689,PMID:9207351,PMID:10443790,PMID:11740736,PMID:11704031,PMID:23375740 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 594 A V cyclopropavir intermediate 4.9 PMID:31940472 CHARMD Fold IC50 values: 4.9, 2.2-4.9; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 +HCMVUL97 X17403.1 594 A V ganciclovir high-level resistance 6.9 PMID:38163624,PMID:7814623,PMID:19063923,PMID:24991428,PMID:24903568,PMID:15230476,PMID:11807689,PMID:20385869,PMID:9207351,PMID:10443790,PMID:11050017,PMID:23985916,PMID:15258973,PMID:15980340,PMID:9129070,PMID:10968438,PMID:15634973,PMID:23375740,PMID:23668613,PMID:26098499,PMID:25130511,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: update 2024 , Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 594 A V maribavir susceptible 1.9 PMID:38163624,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, marker transfer | Observation: Update 2024 IS50 : <2.2 according to Chou 2020 +HCMVUL97 X17403.1 595 L F ganciclovir high-level resistance 6.2 PMID:38163624,PMID:7814623,PMID:24903568,PMID:11807689,PMID:9207351,PMID:26448304,PMID:20138805,PMID:20961907,PMID:11069251,PMID:25143583,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: update 2024 , Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL97 X17403.1 595 L F maribavir susceptible 1.3 PMID:38163624 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL97 X17403.1 595 L L595del ganciclovir high-level resistance 13.3 PMID:7815545,PMID:24903568,PMID:11704031,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 595 L LENGKLTHC595del ganciclovir high-level resistance 8.4 PMID:10096535,PMID:10602745,PMID:24903568 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 595 L S cyclopropavir low-level resistance 2.2 PMID:31940472 CHARMD Fold IC50 values: 2.2, <2.2; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : <2.2 according to Chou 2020 : -HCMVUL97 X17403.1 595 L S ganciclovir high-level resistance 7.5 PMID:38163624,PMID:9207351,PMID:19063923,PMID:24991428,PMID:24903568,PMID:15230476,PMID:11807689,PMID:11050017,PMID:23985916,PMID:18992772,PMID:15980340,PMID:10968438,PMID:23375740,PMID:25130511,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID :udate 2024 , Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 595 L L595del ganciclovir high-level resistance 13.3 PMID:7815545,PMID:24903568,PMID:11704031,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 595 L LENGKLTHC595del ganciclovir high-level resistance 8.4 PMID:10096535,PMID:10602745,PMID:24903568 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 595 L S cyclopropavir low-level resistance 2.2 PMID:31940472 CHARMD Fold IC50 values: 2.2, <2.2; mean displayed | Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : <2.2 according to Chou 2020 +HCMVUL97 X17403.1 595 L S ganciclovir high-level resistance 7.5 PMID:38163624,PMID:9207351,PMID:19063923,PMID:24991428,PMID:24903568,PMID:15230476,PMID:11807689,PMID:11050017,PMID:23985916,PMID:18992772,PMID:15980340,PMID:10968438,PMID:23375740,PMID:25130511,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: udate 2024 , Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL97 X17403.1 595 L S maribavir susceptible 1.3 PMID:38163624 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant -HCMVUL97 X17403.1 595 L W ganciclovir high-level resistance 9 PMID:38163624,PMID:24903568,PMID:11807689,PMID:12198609,PMID:23011309,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID :update 2024 1170403124991428 +HCMVUL97 X17403.1 595 L W ganciclovir high-level resistance 9 PMID:38163624,PMID:24903568,PMID:11807689,PMID:12198609,PMID:23011309,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: update 2024 1170403124991428 HCMVUL97 X17403.1 595 L W maribavir susceptible 1.2 PMID:38163624 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL97 X17403.1 596 E E596del ganciclovir PMID:19704173,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 : -HCMVUL97 X17403.1 596 E G ganciclovir low-level resistance 2.3 PMID:11807689,PMID:19063923,PMID:24903568,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : +HCMVUL97 X17403.1 596 E E596del ganciclovir PMID:19704173,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 +HCMVUL97 X17403.1 596 E G ganciclovir low-level resistance 2.3 PMID:11807689,PMID:19063923,PMID:24903568,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL97 X17403.1 596 E Q ganciclovir low-level resistance 2.7 PMID:37506264 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer -HCMVUL97 X17403.1 596 E Y ganciclovir high-level resistance 6.4 PMID:25750703,PMID:26209398,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 597 N N597del ganciclovir PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : 5-20 according to Chou 2020 : -HCMVUL97 X17403.1 597 N NG597del ganciclovir PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : 5-20 according to Chou 2020 : -HCMVUL97 X17403.1 597 N NGK597del ganciclovir PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : 5-20 according to Chou 2020 : -HCMVUL97 X17403.1 598 G S ganciclovir PMID:9619816,PMID:11888658,PMID:24903568 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Ganciclovir resistance not available -HCMVUL97 X17403.1 599 K E ganciclovir PMID:19704173,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: IS50 : < 2.2 according to Chou 2020 : -HCMVUL97 X17403.1 599 K KLTHC599del ganciclovir high-level resistance 5.3 PMID:9864050,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 599 K R ganciclovir susceptible 1.1 PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : < 2.2 according to Chou 2020 : -HCMVUL97 X17403.1 599 K T ganciclovir high-level resistance 5.3 PMID:9864050,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 600 L I ganciclovir PMID:31940472 CHARMD Observation: IS50 : < 2.2 according to Chou 2020 : -HCMVUL97 X17403.1 600 L L600del ganciclovir susceptible 1.9 PMID:11704031,PMID:24903568,PMID:11807689,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 601 T M ganciclovir PMID:31940472 CHARMD Observation: IS50 : < 2.2 according to Chou 2020 : -HCMVUL97 X17403.1 601 T TH601del ganciclovir high-level resistance 11 PMID:17157554,PMID:24903568,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 601 T THC601del ganciclovir high-level resistance 11 PMID:17157554,PMID:24903568,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 603 C R ganciclovir PMID:12198609,PMID:24903568,PMID:20385869,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 603 C S ganciclovir susceptible 1.9 PMID:12198609,PMID:24903568,PMID:20385869,PMID:20138805 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 603 C W cyclopropavir intermediate 4.9 PMID:31940472 CHARMD Fold IC50 values: 4.9, 2.2-4.9; mean displayed | Source origin: Clinical Isolate | Observation: IS50 : 2.2-4.9 according to Chou 2020 : -HCMVUL97 X17403.1 603 C W ganciclovir high-level resistance 5.9 PMID:38163624,PMID:9063923,PMID:24903568,PMID:15230476,PMID:11807689,PMID:20385869,PMID:12198609,PMID:11595579,PMID:11050017,PMID:23985916,PMID:11740736,PMID:20961907,PMID:11704031,PMID:9291334,PMID:12508158,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : update 202419207351, Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 596 E Y ganciclovir high-level resistance 6.4 PMID:25750703,PMID:26209398,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 597 N N597del ganciclovir PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : 5-20 according to Chou 2020 +HCMVUL97 X17403.1 597 N NG597del ganciclovir PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : 5-20 according to Chou 2020 +HCMVUL97 X17403.1 597 N NGK597del ganciclovir PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : 5-20 according to Chou 2020 +HCMVUL97 X17403.1 598 G S ganciclovir PMID:9619816,PMID:11888658,PMID:24903568 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Ganciclovir resistance not available +HCMVUL97 X17403.1 599 K E ganciclovir PMID:19704173,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: IS50 : < 2.2 according to Chou 2020 +HCMVUL97 X17403.1 599 K KLTHC599del ganciclovir high-level resistance 5.3 PMID:9864050,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 599 K R ganciclovir susceptible 1.1 PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Observation: IS50 : < 2.2 according to Chou 2020 +HCMVUL97 X17403.1 599 K T ganciclovir high-level resistance 5.3 PMID:9864050,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 600 L I ganciclovir PMID:31940472 CHARMD Observation: IS50 : < 2.2 according to Chou 2020 +HCMVUL97 X17403.1 600 L L600del ganciclovir susceptible 1.9 PMID:11704031,PMID:24903568,PMID:11807689,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 601 T M ganciclovir PMID:31940472 CHARMD Observation: IS50 : < 2.2 according to Chou 2020 +HCMVUL97 X17403.1 601 T TH601del ganciclovir high-level resistance 11 PMID:17157554,PMID:24903568,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 601 T THC601del ganciclovir high-level resistance 11 PMID:17157554,PMID:24903568,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 603 C R ganciclovir PMID:12198609,PMID:24903568,PMID:20385869,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 603 C S ganciclovir susceptible 1.9 PMID:12198609,PMID:24903568,PMID:20385869,PMID:20138805 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 603 C W cyclopropavir intermediate 4.9 PMID:31940472 CHARMD Fold IC50 values: 4.9, 2.2-4.9; mean displayed | Source origin: Clinical Isolate | Observation: IS50 : 2.2-4.9 according to Chou 2020 +HCMVUL97 X17403.1 603 C W ganciclovir high-level resistance 5.9 PMID:38163624,PMID:9063923,PMID:24903568,PMID:15230476,PMID:11807689,PMID:20385869,PMID:12198609,PMID:11595579,PMID:11050017,PMID:23985916,PMID:11740736,PMID:20961907,PMID:11704031,PMID:9291334,PMID:12508158,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: update 202419207351, Mutation frequently found in patients receiving hematopoietic stem cells HCMVUL97 X17403.1 603 C W maribavir susceptible 1.2 PMID:38163624 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant HCMVUL97 X17403.1 603 C Y ganciclovir low-level resistance 2.8 PMID:38163624 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer HCMVUL97 X17403.1 603 C Y maribavir susceptible 0.89 PMID:38163624 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant -HCMVUL97 X17403.1 607 C F ganciclovir susceptible 1.9 PMID:11740736,PMID:24903568,PMID:11807689,PMID:23985916 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : -HCMVUL97 X17403.1 607 C Y ganciclovir high-level resistance 12.5 PMID:11740736,PMID:24903568,PMID:11807689,PMID:12198609,PMID:26098499,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Other publication ID : Mutation frequently found in patients receiving hematopoietic stem cells -HCMVUL97 X17403.1 610 I T ganciclovir low-level resistance 2.6 PMID:25750703,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 : -HCMVUL97 X17403.1 613 A V ganciclovir low-level resistance 2.3 PMID:24120366,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 : +HCMVUL97 X17403.1 607 C F ganciclovir susceptible 1.9 PMID:11740736,PMID:24903568,PMID:11807689,PMID:23985916 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer +HCMVUL97 X17403.1 607 C Y ganciclovir high-level resistance 12.5 PMID:11740736,PMID:24903568,PMID:11807689,PMID:12198609,PMID:26098499,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: Mutation frequently found in patients receiving hematopoietic stem cells +HCMVUL97 X17403.1 610 I T ganciclovir low-level resistance 2.6 PMID:25750703,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 +HCMVUL97 X17403.1 613 A V ganciclovir low-level resistance 2.3 PMID:24120366,PMID:31940472 CHARMD Source origin: Laboratory strain, Clinical Isolate | Marker transfer: Recombinant | Assay details: PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer | Observation: IS50 : 2.2-4.9 according to Chou 2020 HCMVUL97 X17403.1 615 M V brincidofovir sensitive PMID:21570426 CHARMD Source origin: naive patient | Observation: Natural polymorphism HCMVUL97 X17403.1 615 M V cidofovir sensitive PMID:21570426 CHARMD Source origin: naive patient | Observation: Natural polymorphism HCMVUL97 X17403.1 615 M V cyclopropavir sensitive PMID:21570426 CHARMD Source origin: naive patient | Observation: Natural polymorphism diff --git a/databases/charmd/scripts/convert.py b/databases/charmd/scripts/convert.py index 2ef0938..8e4e87b 100644 --- a/databases/charmd/scripts/convert.py +++ b/databases/charmd/scripts/convert.py @@ -345,8 +345,10 @@ def parse_fold_ic50(raw: str) -> tuple[float | None, str]: def publication_values(row: dict[str, str]) -> list[str]: # PMIDs from the dedicated pubmed_id column plus any cross-referenced in - # the observation field ("Autre publi ID : ..."). Both sources are - # merged so a rule carries every supporting publication. + # the observation field ("Other publication ID : ..."). Both + # sources are merged so a rule carries every supporting publication. + # The scan is a plain digit match over the whole observation, so it is + # independent of the label wording. tokens = re.findall(r"\b\d{7,9}\b", norm(row.get("pubmed_id"))) tokens.extend(re.findall(r"\b\d{7,9}\b", norm(row.get("observation")))) return [f"PMID:{token}" for token in tokens] @@ -364,13 +366,17 @@ def row_comment(row: dict[str, str]) -> str: parts.append(f"{label}: {value}") # The observation column is unstructured free text that often carries - # cross-referenced PMIDs ("Autre publi ID"). Those are harvested into the - # publication column by publication_values(); the residual text (clinical - # context, alternative fold values, curation notes) is recorded here. + # cross-referenced PMIDs ("Other publication ID"). Those are harvested + # into the publication column by publication_values(); the residual text + # (clinical context, alternative fold values, curation notes) is recorded + # here. The label itself is stripped so it does not leak into comments. observation = clean_text(row.get("observation")) if observation: - residual = re.sub(r"Autre publi ID\s*:", "", observation) + residual = re.sub(r"Other publication\s*ID\s*:?", "", observation) residual = re.sub(r"\b\d{7,9}\b", "", residual) + # Digit removal can leave orphan separators (",", ":") between the + # stripped label and residual text; drop leading/trailing ones. + residual = re.sub(r"^[\s,:;]+|[\s,:;]+$", "", residual) residual = clean_text(residual) if residual: parts.append(f"Observation: {residual}")